Omeprazole enteric-coated capsules

Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells and converted into the active form of sulfenamide in this high-acid environment. It then irreversibly combines with the sulfhydryl group of the H,K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.

Omeprazole. Chemical name: 5-methoxy-2-{[(4-methoxy-3,5-dimethyl-2-pyridyl)-methyl]-sulfoxide}-1H-benzimidazole. Molecular formula: C17H19N3O3S Molecular weight: 345.41

The content of this product is white or off-white enteric-coated granules.

Duodenal ulcer, gastric ulcer, reflux esophagitis, Zollinger-Ellison syndrome.

pOral administration, do not chew. 1Peptic ulcer: 20 mg (1 tablet at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course for gastric ulcer is usually 4-8 weeks, and the treatment course for duodenal ulcer is usually 2-4 weeks; 2Reflux esophagitis: 20-60 mg (1-3 tablets at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course is usually 4-8 weeks; 3Zollinger-Ellison syndrome: 60 mg (3 tablets at a time), once a day. The total daily dose can be adjusted to 20-120 mg (1-6 tablets) according to the condition. If the total daily dose exceeds 80 mg (4 tablets), it should be taken in two doses.

This product is well tolerated. Common adverse reactions include diarrhea, headache, nausea, abdominal pain, flatulence and constipation. Occasionally, serum aminotransferase (ALT, AST) increases, rash, dizziness, drowsiness, insomnia, etc. These adverse reactions are usually mild, disappear automatically, and are not related to the dose. No serious adverse reactions have been observed in long-term treatment, but gastric mucosal cell hyperplasia and atrophic gastritis may occur in some cases.

It is contraindicated for patients who are allergic to this product, those with severe renal insufficiency and infants.

Precautions for children: It is forbidden for infants and young children. Precautions for pregnancy and lactation: Although this product has no teratogenic effect in animal experiments, it should generally not be used by pregnant women, and should also be used with caution for lactating women. Precautions for the elderly: It is not clear yet.

This product can delay the elimination of drugs metabolized by the liver in the body, such as diazepam, phenytoin sodium, warfarin, nifedipine, etc. When this product is used together with the above-mentioned drugs, the dosage of the latter should be reduced.

Protect from light, seal tightly, and store in a cool and dry place.

20mg

24 months.

Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.

• Founded in:

  2000-09-29

• Address:

  No. 88 Tianxing Avenue, Qionglai City, Sichuan Province

• Tax NO.:

  915101832024104543

• Registered Funds:

  75 million yuan

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