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Terazosin Hydrochloride Tablets

Function and Efficacy

This product is a selective α1 receptor blocker that can reduce peripheral vascular resistance and has a lowering effect on both systolic and diastolic blood pressure; it has the effect of relaxing bladder and prostate smooth muscles and can relieve symptoms of dysuria caused by benign prostatic hypertrophy.

Ingredients

The main ingredient of this product is: terazosin hydrochloride. Its chemical name is: 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydrofuran-2-formyl)piperazine, monohydrochloride dihydrate.

Name Description Content CAS NO. Manufacturer
Terazosin hydrochlorideIngredients

This product is a selective α1 receptor blocker that can reduce peripheral vascular resistance and has a lowering effect on both systolic and diastolic blood pressure; it has the effect of relaxing bladder and prostate smooth muscles and can relieve symptoms of dysuria caused by benign prostatic hypertrophy.

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63074-08-8 18

Appearance

This product is yellow flat round tablets.

Indication

1. Used to treat hypertension, can be used alone or in combination with other antihypertensive drugs. 2. Used to improve urination symptoms in patients with benign prostatic hyperplasia, such as frequent urination, urgency, thinning of urine stream, difficulty urinating, increased nocturia, feeling of incomplete urination, etc.

Usage and Dosage

Oral. Hypertensive patients: once a day, first before bedtime. The starting dose is 1 mg, and the dose is gradually increased until a satisfactory effect is achieved. The common dose is 1-10 mg a day, and the maximum dose is 20 mg a day. If treatment needs to be restarted after discontinuation of the drug, the dose must also be gradually increased from 1 mg. Patients with benign prostatic hyperplasia: once a day, 2 mg each time, before bedtime every night.

Adverse Reactions

The main adverse reactions of this product are: headache, dizziness, weakness, palpitations, nausea, postural hypotension, etc. These reactions are usually mild and will disappear on their own with continued treatment. The dosage can be reduced if necessary.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not clear. Precautions for pregnancy and lactation: Pregnant women are prohibited from using this product. Lactating women should stop breastfeeding when using this product. Precautions for the elderly: Pharmacokinetic studies have shown that the recommended dose does not need to be changed when the elderly use this product. Elderly patients are more likely to develop orthostatic hypotension than younger patients when using terazosin to treat benign prostatic hyperplasia.

Drug Interactions

In clinical trials, the proportion of patients who reported dizziness or other related adverse reactions in patients treated with this product and angiotensin (ACE) inhibitors or diuretics was higher than the proportion of all patients treated with this product. When this product is used in combination with other antihypertensive drugs, care should be taken to avoid significant hypotension. When this product is added to diuretics or other antihypertensive drugs, the dose should be reduced and re-established if necessary. This product is known to have no interaction with analgesics/anti-inflammatory drugs, cardiac glycosides, hypoglycemic drugs, antiarrhythmic drugs, antianxiety drugs/sedatives, antibacterial drugs, hormones/steroids and gout drugs. There are reports that hypotension may occur when this product is used in combination with phosphodiesterase (PDE-5) inhibitors.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

2mg (based on C19H25N5O4)

Validity Period

36 months

Manufacturer

Yangzhou Ilyang Pharm. Co., Ltd.

  • Founded in:

    2002-02-10
  • Address:

    No. 8 Changxing Road, Gaoyou City
  • Tax NO.:

    913210846087092887
  • Registered Funds:

    $6.25 million
  • Website:

  • Email:

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