Lithium carbonate tablets
Function and Efficacy
This product works in the form of lithium ions. Its mechanism of anti-manic attacks is to inhibit the Ca2-dependent release of norepinephrine and dopamine from nerve endings, promote the reuptake of norepinephrine in the synaptic cleft by nerve cells, increase its conversion and inactivation, thereby reducing the concentration of norepinephrine, and promote the synthesis and release of 5-hydroxytryptamine, which helps stabilize emotions. This product has many adverse reactions, but it is still the first choice for the treatment of mania.
Ingredients
The main ingredient of this product and its chemical name is: lithium carbonate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Lithium carbonateIngredients |
This product works in the form of lithium ions. Its mechanism of preventing manic attacks is to inhibit the Ca2-dependent release of norepinephrine and dopamine from nerve endings, promote the reuptake of norepinephrine in the synaptic cleft by nerve cells, increase its conversion and inactivation, thereby reducing the concentration of norepinephrine. It can also promote the synthesis and release of serotonin, which helps stabilize mood. More |
554-13-2 | 25 |
Appearance
This product is white or off-white tablets.
Indication
It is mainly used to treat mania, and has a good effect on treating and preventing relapses of bipolar disorder with alternating manic and depressive episodes, and also has a preventive effect on recurrent depression. It is also used to treat schizoaffective psychosis.
Usage and Dosage
The oral dose should be gradually increased and adjusted according to the blood lithium concentration. During the treatment period, the dose is 0.9-1.5 g (3-5 tablets) per day, taken in 1-2 times. For maintenance treatment, the dose is 0.6-0.9 g (2-3 tablets) per day.
Adverse Reactions
Common adverse reactions include dry mouth, thirst, polydipsia, polyuria, constipation, diarrhea, nausea, vomiting, and upper abdominal pain. Adverse reactions of the nervous system include fine tremors in both hands, malaise, weakness, drowsiness, blurred vision, and hyperreflexia of tendons. It can cause an increase in white blood cells. Aggravation of the above adverse reactions may be a precursor to poisoning and should be closely observed.
Precautions
It is contraindicated in patients with renal insufficiency or severe heart disease.
Drug Interactions
1. When this product is used in combination with aminophylline, caffeine or sodium bicarbonate, it can increase the urine excretion of this product, reduce the blood concentration and efficacy. 2. When this product is used in combination with chlorpromazine and other phenothiazine derivatives, the blood concentration of chlorpromazine can be reduced. 3. When this product is used in combination with iodide, it can induce hypothyroidism. 4. When this product is used in combination with norepinephrine, the latter's pressor effect is reduced. 5. When this product is used in combination with muscle relaxants (such as succinylcholine, etc.), the muscle relaxant effect is enhanced and the duration of action is prolonged. 6. When this product is used in combination with piroxicam, it can lead to excessive blood lithium concentration and poisoning.
Storage
Keep sealed.
Packaging Specification
0.25g
Manufacturer
Sichuan Chuanda West China Pharmaceutical Co., Ltd.
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Founded in:
2003-12-26 -
Address:
No. 530, Building 2, No. 33, Wuqing South Road, Wuhou District, Chengdu -
Tax NO.:
91510000756621499A -
Registered Funds:
80 million yuan -
Website:
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Email: