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Nifedipine extended-release tablets

Function and Efficacy

Nifedipine (NF) inhibits the influx of calcium ions into cells by blocking the membrane transport of calcium ions in myocardial and vascular smooth muscle, causing decreased myocardial contractility and vasodilation. Animal experiments have shown that by reducing myocardial contractility and peripheral vascular resistance, myocardial oxygen consumption is reduced; by dilating coronary vessels and developing collateral circulation, oxygen supply to myocardial ischemic sites is increased; by inhibiting the consumption of high-energy phosphate compounds, the ability to resist hypoxia is enhanced.

Ingredients

The main ingredient of this product is nifedipine.

Name Description Content CAS NO. Manufacturer
NifedipineIngredients

By blocking the membrane transport of calcium ions in myocardial and vascular smooth muscle, it inhibits the influx of calcium ions into cells, causing a decrease in myocardial contractility and vasodilation. Animal experiments have shown that by reducing myocardial contractility and peripheral vascular resistance, myocardial oxygen consumption is reduced; by dilating coronary vessels and developing collateral circulation, the oxygen supply to myocardial ischemic sites is increased; by inhibiting the consumption of high-energy phosphate compounds, the ability to resist hypoxia is enhanced.

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21829-25-4 75

Appearance

This product is a film-coated tablet, which appears yellow after removing the film coating.

Indication

Usage and Dosage

Oral, once a day, the initial dose is 20 mg (1 tablet) each time. Depending on the condition and under the guidance of a doctor, it can be increased to 40-60 mg each time. This product cannot be chewed or broken when taken.

Adverse Reactions

1. Liver: Occasionally, jaundice and elevated glutamic acid oxaloacetic acid aminotransferase and glutamic acid pyruvic acid aminotransferase may occur. 2. Circulatory system: Occasionally, chest pain, headache, flushing, dizziness, palpitations, decreased blood pressure, lower limb edema may occur. 3. Allergies: Occasionally, allergic symptoms such as measles and itching may occur. 4. Digestive system: Occasionally, abdominal pain, nausea, loss of appetite, constipation may occur. 5. Oral cavity: Gum hypertrophy may occur. 6. Metabolic abnormalities: Occasionally, symptoms of hyperglycemia may occur.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Children are prohibited from using. Precautions for pregnancy and lactation: Precautions for pregnant and lactating women are prohibited. Precautions for the elderly: See [Usage and Dosage] or follow the doctor's advice.

Drug Interactions

This experiment has not been conducted and there are no reliable references.

Storage

Keep away from light and store in sealed container.

Packaging Specification

10 mg

Validity Period

Tentative 24 months

Manufacturer

Hunan Warrant Pharmaceutical Co., Ltd.

  • Founded in:

    2001-04-30
  • Address:

    Hunan Liuyang Biomedicine Park
  • Tax NO.:

    914301007279773228
  • Registered Funds:

    93.8 million yuan
  • Website:

  • Email:

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