Gentamycin Sulfate Tablets

This product is an aminoglycoside antibiotic. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good antibacterial effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has a certain effect on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has a good antibacterial effect on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococcus), but methicillin-resistant strains are mostly resistant to this product. It has a poor effect on Streptococcus and Streptococcus pneumoniae, and Enterococcus is mostly resistant to this product. When this product is used in combination with beta-lactams, most of them can obtain synergistic antibacterial effects. The mechanism of action of this product is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins. In recent years, the number of Gram-negative bacteria resistant to gentamicin has increased significantly.

The main ingredient of this product is gentamicin sulfate, which is a multi-component antibiotic containing components such as C1, C1a, C2a, and C2.

This product is suitable for the treatment of bacterial dysentery or other bacterial intestinal infections, and can also be used for preparation before colon surgery.

Oral administration: Adults: 240-640 mg per day, divided into 4 doses; children: 5-10 mg/kg per day, divided into 4 doses.

A small number of patients may experience loss of appetite, nausea, diarrhea, etc. after taking the medicine.

Patients who are allergic to this product or other aminoglycoside antibiotics are contraindicated.

1. When used in combination with other aminoglycosides or when applied topically or systemically successively, it may increase the possibility of producing ototoxicity, nephrotoxicity and neuromuscular blocking effects. 2. When used in combination with neuromuscular blockers, it may aggravate neuromuscular blocking effects, leading to symptoms such as muscle weakness and respiratory depression. 3. When used in combination with capreomycin, cisplatin, ethacrynic acid, furosemide or vancomycin (or norvancomycin), or when applied topically or systemically successively, it may increase ototoxicity and nephrotoxicity. 4. When used topically or systemically with cephalothin or cefazolin, it may increase nephrotoxicity. 5. When used in combination with polymyxin injections or when applied topically or systemically successively, it may increase nephrotoxicity and neuromuscular blocking effects. 6. Other nephrotoxic and ototoxic drugs should not be used in combination with this product or applied topically successively, so as not to aggravate nephrotoxicity or ototoxicity.

Sealed, store in a cool, dark and dry place.

40mg (40,000 units)

Guangdong Wuzhou Pharmaceutical Co., Ltd.

• Founded in:

  2003-04-02

• Address:

  No. 1, Gongye South Road, Private Technology Industrial Park, Suixi County, Zhanjiang City

• Tax NO.:

  91440823748047546G

• Registered Funds:

  10 million yuan

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