Cinnarizine Tablets
Function and Efficacy
This product is a piperazine calcium channel antagonist, which can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the concentration of cAMP in cells, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4. The lethal dose for humans is 100-500 mg/kg, and the LD50 (oral administration to mice and rats) is greater than 1g/kg.
Ingredients
Cinnarizine
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| StugeronIngredients |
This product is a piperazine calcium channel antagonist that can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the intracellular cAMP concentration, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4. More |
298-57-7 | 15 |
Appearance
This product is white or off-white tablets.
Indication
For cerebral thrombosis, cerebral embolism, brain<Aclass=bluehref=http://jbk.39.net/keshi/neike/xxgnk/49039.htmltarge
Usage and Dosage
Oral administration, 25-50 mg each time, 3 times a day.
Adverse Reactions
Common symptoms include drowsiness, fatigue, and weight gain in some patients (generally transient). Long-term use may occasionally cause depression and extrapyramidal reactions, such as bradykinesia, rigidity, akathisia, dry mouth, muscle pain, and rash.
Precautions
Patients with a history of allergy to this drug or a history of depression are contraindicated using this drug.
Special Population Medication
Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: follow doctor's advice. Precautions for the elderly: follow doctor's advice.
Drug Interactions
1. When used in combination with alcohol, hypnotics or sedatives, the sedative effect is aggravated. 2. When used in combination with phenytoin sodium and carbamazepine, the blood concentration of cinnarizine can be reduced.
Storage
Shade, sealed and stored
Packaging Specification
25mg
Validity Period
24 months
Manufacturer
Guangdong P.D.Pharmaceutical Co., Ltd.
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Founded in:
1994-08-15 -
Address:
No. 66, Bidi Avenue, Yueshan Town, Kaiping City, Guangdong Province -
Tax NO.:
91440700617754849P -
Registered Funds:
$6 million -
Website:
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Email: