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Cinnarizine Tablets

Function and Efficacy

This product is a piperazine calcium channel antagonist, which can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the concentration of cAMP in cells, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4. The lethal dose for humans is 100-500 mg/kg, and the LD50 (oral administration to mice and rats) is greater than 1g/kg.

Ingredients

Cinnarizine

Name Description Content CAS NO. Manufacturer
StugeronIngredients

This product is a piperazine calcium channel antagonist that can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the intracellular cAMP concentration, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4.

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298-57-7 15

Appearance

This product is white or off-white tablets.

Indication

For cerebral thrombosis, cerebral embolism, brain<Aclass=bluehref=http://jbk.39.net/keshi/neike/xxgnk/49039.htmltarge

Usage and Dosage

Oral administration, 25-50 mg each time, 3 times a day.

Adverse Reactions

Common symptoms include drowsiness, fatigue, and weight gain in some patients (generally transient). Long-term use may occasionally cause depression and extrapyramidal reactions, such as bradykinesia, rigidity, akathisia, dry mouth, muscle pain, and rash.

Precautions

Patients with a history of allergy to this drug or a history of depression are contraindicated using this drug.

Special Population Medication

Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: follow doctor's advice. Precautions for the elderly: follow doctor's advice.

Drug Interactions

1. When used in combination with alcohol, hypnotics or sedatives, the sedative effect is aggravated. 2. When used in combination with phenytoin sodium and carbamazepine, the blood concentration of cinnarizine can be reduced.

Storage

Shade, sealed and stored

Packaging Specification

25mg

Validity Period

24 months

Manufacturer

Guangdong P.D.Pharmaceutical Co., Ltd.

  • Founded in:

    1994-08-15
  • Address:

    No. 66, Bidi Avenue, Yueshan Town, Kaiping City, Guangdong Province
  • Tax NO.:

    91440700617754849P
  • Registered Funds:

    $6 million
  • Website:

  • Email:

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