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Nicergoline for injection

Function and Efficacy

This product is a semi-synthetic ergot alkaloid derivative. It has α receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It can promote the conversion of neurotransmitter dopamine to enhance nerve conduction, strengthen brain protein biosynthesis, and improve brain function. Toxicity tests failed to show that nicergoline has teratogenic effects.

Ingredients

Nicergoline

Name Description Content CAS NO. Manufacturer
NicergolineIngredients

This product is a semi-synthetic ergot alkaloid derivative. It has α receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It can promote the conversion of neurotransmitter dopamine to enhance nerve conduction, strengthen brain protein biosynthesis, and improve brain function. Toxicity tests failed to show that nicergoline has teratogenic effects.

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27848-84-6 35

Appearance

This product is white or off-white loose mass or powder.

Indication

1. Improve the low will and emotional disorders caused by the sequelae of cerebral infarction (slow sensation, lack of concentration, memory loss, lack of ideas, depression, anxiety, etc.). 2. Acute and chronic peripheral circulatory disorders (limb vascular occlusive disease, Raynaud's syndrome, other symptoms of poor peripheral circulation).

Usage and Dosage

Intramuscular injection: 2-4 mg each time, twice a day. Intravenous drip: 4-8 mg each time, dissolved in 100 ml of normal saline or glucose injection and slowly dripped, 1-2 times a day. Arterial injection: 4 mg each time, dissolved in 10 ml of normal saline and slowly injected (2 minutes).

Adverse Reactions

No serious adverse reactions have been reported. There may be hypotension, dizziness, stomach pain, hot flashes, facial flushing, drowsiness, insomnia, etc. In clinical trials, an increase in uric acid concentration in the blood was observed, but this phenomenon was not related to the dosage and administration time.

Precautions

This product is contraindicated in the following cases: those who are allergic to nicergoline, recent myocardial infarction, acute bleeding, hypotension, severe bradycardia, orthostatic regulation dysfunction, and bleeding tendency.

Drug Interactions

Nicergoline tablets may enhance the effects of antihypertensive drugs. Since nicergoline is metabolized by CYTP4502D6, interactions with drugs that are metabolized by the same pathway cannot be ruled out.

Storage

Keep in a sealed container and away from light.

Packaging Specification

2mg

Manufacturer

Ma'anshan Fengyuan Pharmaceutical Co., Ltd.

  • Founded in:

    2008-06-26
  • Address:

    No. 1503, Meishan Road, Economic and Technological Development Zone, Ma'anshan City, Anhui Province
  • Tax NO.:

    913405006758985090
  • Registered Funds:

    145.5 million yuan
  • Email:

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