Doxycycline Hydrochloride Tablets

Tetracycline antibiotics. This product is a broad-spectrum antibacterial agent with bactericidal effects at high concentrations. Many Rickettsia, Mycoplasma, Chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product is better than Gram-positive bacteria for Gram-negative bacteria, but Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, and Yersinia are sensitive to this product. This product has certain antibacterial activity against Neisseria gonorrhoeae, but penicillin-resistant Neisseria gonorrhoeae is also resistant to doxycycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have become seriously resistant to this product, including Gram-positive bacteria such as Staphylococcus and most Gram-negative bacilli. There is cross-resistance between this product and different varieties of tetracycline antibiotics. The mechanism of action of this product is that the drug can specifically bind to the A position of the bacterial ribosome 30S subunit, inhibiting the growth of the peptide chain and affecting the synthesis of bacterial protein. Animal experiments have confirmed that this product is teratogenic. In vitro tests have shown that this product may be mutagenic at a certain concentration.

Doxycycline hydrochloride.

This product is light yellow tablet.

No data yet

Antibacterial and antiparasitic infections: Adults, 100 mg on the first day, once every 12 hours, followed by 100-200 mg once a day, or 50-100 mg once every 12 hours. Gonorrheal Neisseria urethritis and cervicitis: 100 mg once every 12 hours. For a total of 7 days. Non-gonococcal Neisseria urethritis, caused by Chlamydia trachomatis or Ureaplasma urealyticum, and simple urethritis, cervicitis or rectal infection caused by Chlamydia trachomatis: 100 mg once, twice a day, for a course of at least 7 days. Syphilis: 150 mg once, once every 12 hours, for a course of at least 10 days. Children over 8 years old: 2.2 mg/kg of body weight once every 12 hours on the first day, followed by 2.2-4.4 mg/kg of body weight once a day, or 50-100 mg once every 12 hours.

1. Digestive system: Oral administration of this product may cause gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. Occasionally, there have been reports of esophagitis and esophageal ulcers, which mostly occur in patients who are bedridden immediately after taking the drug. 2. Hepatotoxicity: It is prone to occur in patients with fatty liver degeneration and pregnant women, and it can also occur in patients without the above conditions. Occasionally, pancreatitis may occur. Pancreatitis caused by this product may also occur simultaneously with hepatotoxicity, and the patient does not have primary liver disease. 3. Allergic reactions: Mostly maculopapular rash and erythema, a few patients may have urticaria, angioneurotic edema, allergic purpura, pericarditis, and aggravation of skin lesions of systemic lupus erythematosus, and exfoliative dermatitis is not common. Occasionally, anaphylactic shock and asthma occur. Some patients who use this product may have photosensitivity when exposed to the sun. Therefore, it is recommended that patients should not be directly exposed to sunlight or ultraviolet rays while taking this product, and the drug should be stopped immediately if erythema appears on the skin. 4. Blood system: Occasionally it may cause hemolytic anemia, thrombocytopenia, neutropenia and eosinophilia. 5. Central nervous system: Occasionally it may cause benign intracranial hypertension, which may manifest as headache, vomiting, papilledema, etc., which may be relieved after stopping the drug. 6. Double infection: Long-term use of this product may cause digestive tract, respiratory tract and urinary tract infections caused by drug-resistant Staphylococcus aureus, Gram-negative bacteria and fungi, and in severe cases may cause sepsis. 7. The use of tetracyclines can reduce the normal flora in the human body, and cause vitamin deficiency, fungal growth, dry mouth, pharyngitis, angular cheilitis and glossitis.

Patients with a history of allergy to tetracyclines are contraindicated.

Precautions for children: Children under 8 years old are prohibited to use. Precautions for pregnancy and lactation: This product can enter the fetus through the placental barrier and deposit in the calcium area of teeth and bones, causing fetal tooth discoloration, poor enamel regeneration and inhibiting fetal bone growth. This type of drug has teratogenic effects in animal experiments, so pregnant women should not use it. This product can be secreted from breast milk, and the concentration in breast milk is relatively high. Lactating women should stop breastfeeding when using it. Precautions for the elderly: Not yet clear.

Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.

seal.

20mg (calculated as C22H24N2O8)

24 months

Jiangxi Qingfeng Pharmaceutical Co., Ltd.

• Founded in:

  2001-12-12

• Address:

  Shahe Industrial Park, Zhanggong District, Ganzhou City, Jiangxi Province

• Tax NO.:

  91360702744263663W

• Registered Funds:

  250.27681367 yuan

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