Taysuda (piribedil extended-release tablets)
Function and Efficacy
Peripheral vasodilators (C: cardiovascular system) Anti-Parkinson drugs (N: nervous system) Pharmacodynamic characteristics: Piribedil: Dopaminergic agonist (stimulates dopamine receptors and dopaminergic pathways in the brain) In humans, clinical pharmacology studies have clarified its mechanism of action.
Ingredients
Each tablet of Taishu 50mg sustained-release coated tablet contains 50mg of piribedil. Chemical name: [(methylenetrioxy-3,4-benzyl)-4-piperazinyl-1]-2-pyrimidine Molecular weight: C16H18N4O2
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| 2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidineIngredients |
Peripheral vasodilator; antiparkinsonian drug; dopaminergic agonist (stimulates dopamine receptors and dopaminergic pathways in the brain) More |
3605-01-4 | 6 |
Appearance
This product is a red sustained-release coated tablet, which appears white after removing the coating.
Indication
As a monotherapy or in combination with levodopa, it is used to treat Parkinson's disease, improve pathological cognitive and sensory neurological dysfunction in elderly patients, such as decreased attention and/or memory, vertigo. Painful symptoms of arterial lesions (painful cramps when walking). Ophthalmological disorders of circulatory origin.
Usage and Dosage
1. Parkinson's disease: 150-250 mg per day, divided into 3-5 times. 2. Combined with levodopa: 50-150 mg per day, divided into 1-3 times. 3. Other indications: 50 mg per day, taken after the main meal. 4. Severe cases: 100 mg per day, divided into 2 times.
Adverse Reactions
The following symptoms may occur: 1. Mild gastrointestinal discomfort (nausea, vomiting, flatulence), which may disappear after individualized dosage adjustment. 2. There have been reports of drowsiness after taking piribedil. In very few individuals, excessive drowsiness and sudden falling asleep during the day have occurred. 3. Psychological disorders such as confusion or agitation may also occur, although they are relatively rare. These symptoms may disappear after discontinuation of the drug. 4. Blood pressure disorders (orthostatic hypotension) or unstable blood pressure are very rare. 5. Because it contains carmine, it may cause allergic reactions. If any adverse events and/or adverse reactions outside of this instruction manual occur after taking this drug, please contact your doctor.
Precautions
This drug is contraindicated in the following cases: 1. Allergic to any ingredient in this product. 2. Cardiovascular shock. 3. Acute myocardial infarction. 4. Combined medication: antiemetic neuroleptics, tranquilizers (excluding clozapine) (except Parkinson's patients).
Special Population Medication
Precautions for children: The safety and effectiveness of the drug for children have not been determined. Precautions for pregnancy and lactation: This drug is absolutely limited to elderly patients and people who are not at risk of pregnancy. In the absence of relevant information, it is not recommended for use in pregnant and lactating women. Precautions for the elderly: See the content under other items, or follow the doctor's advice.
Drug Interactions
Contraindications for combined use 1. Tranquilizers (excluding clozapine) (In non-Parkinson's patients) There is an antagonism between dopamine agonists and neuroleptics. When extrapyramidal symptoms occur due to taking tranquilizers, patients should not be treated with dopamine agonists, but anticholinergic drugs should be used. 2. Antiemetics There is an antagonism between dopamine agonists and neuroleptics. Antiemetics without extrapyramidal effects should be used. Inappropriate combined use 3. Tranquilizers (excluding clozapine) (In Parkinson's patients) There is an antagonism between dopamine agonists and neuroleptics. Dopamine agonists can cause or aggravate mental disorders. If you are currently using dopamine agonists for treatment
Storage
Keep away from light and store in a sealed container.
Packaging Specification
50mg*15s
Validity Period
36 months