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Metronidazole suppositories

Function and Efficacy

This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica amoeba can undergo morphological changes in 6~20 hours and all are killed within 24 hours. When the concentration is 0.2mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on cells and anaerobic microorganisms growing under hypoxic conditions. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death.

Ingredients

Metronidazole.

Name Description Content CAS NO. Manufacturer
MetronidazoleIngredients

This product is a nitroimidazole derivative that can inhibit the redox reaction of amoeba and break the nitrogen chain of the protozoa. In vitro tests have shown that when the drug concentration is 1~2mg/L, the histolytica amoeba can undergo morphological changes in 6~20 hours and all are killed within 24 hours. When the concentration is 0.2mg/L, the histolytica amoeba can be killed within 72 hours. This product has a strong effect of killing trichomonas, and its mechanism is unknown. Metronidazole has a killing effect on cells and anaerobic microorganisms growing under hypoxic conditions. The metabolites generated when it is reduced in the human body also have anti-anaerobic effects, inhibiting the synthesis of bacterial deoxyribonucleic acid, thereby interfering with the growth and reproduction of bacteria, and ultimately causing bacterial death.

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443-48-1 39

Appearance

This product is a milky white to light yellow torpedo-shaped suppository.

Indication

It is used to treat Trichomonas vaginitis. It can also be used to prevent and treat anaerobic infection after minor gynecological surgery.

Usage and Dosage

Vaginal administration: 0.5g at a time, 0.5g once every night, for 7 to 10 days. Metronidazole tablets should be taken at the same time, 0.2g each time, four times a day, for seven consecutive days.

Adverse Reactions

Same as tablets.

Precautions

It is forbidden to use in pregnant and lactating women.

Special Population Medication

Precautions for children: This test has not been conducted and there is no reference literature. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: This test has not been conducted and there is no reference literature.

Drug Interactions

Not yet clear.

Storage

Keep in a dark place, sealed and stored in a cool place below 30℃

Packaging Specification

0.5g

Validity Period

36 months.

Manufacturer

Guangxi Shiwanshan Pharmaceutical Co., Ltd.

  • Founded in:

    2002-10-25
  • Address:

    Southern Suburbs of Shangsi County
  • Tax NO.:

    91450621742089059K
  • Registered Funds:

    68.5 million yuan
  • Email:

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