progesterone capsules

Progesterone is a steroid hormone secreted by the ovary, placenta and adrenal glands. In the presence of sufficient estrogen, progesterone can change the endometrium from the proliferative phase to the secretory phase, providing favorable conditions for the implantation of the fertilized egg. After the implantation of the fertilized egg, the placenta is formed, which can reduce the excitability of the pregnant uterus and maintain the pregnancy state; it can promote breast development and prepare for lactation. This product can inhibit the release of luteinizing hormone from the anterior pituitary through negative feedback to the hypothalamus, so that the follicles cannot mature and inhibit the ovulation process of the ovary. The median lethal dose of this product in mice is 6.2869 (5.2154-7.5785) g/kg, which is equivalent to 3 times the clinical dosage.

The main component of this product is progesterone, and its chemical name is: pregnane-4-ene-3,20-dione.

This product is a soft capsule, the contents of which are off-white or light yellow thick emulsion.

Threatened abortion and habitual abortion, premenstrual tension syndrome, anovulatory functional uterine bleeding and anovulatory amenorrhea, used in combination with estrogen to treat menopausal syndrome.

1. Used in combination with estrogen (such as conjugated estrogen, Premarin). Premarin tablets: Oral, 1.25 mg, once a day, for 22 days. Take this product from 13 days after taking Premarin tablets, orally, 200 mg (2 tablets) each time, twice a day, for 10 days. 2. For the treatment of threatened abortion and habitual abortion, premenstrual syndrome, anovulatory blood supply and ovulatory amenorrhea, the general routine dosage is 200-300 mg (2-3 tablets) per day, taken once or twice, and each dose should not exceed 200 mg (2 tablets). Try to take the medicine away from meal times.

Breakthrough bleeding, vaginal spotting, weight gain or loss, changes in the cervical squamous-columnar junction, changes in cervical discharge, breast swelling, nausea, dizziness, headache, malaise, fever, insomnia, allergic rash with or without itching, melasma, chloasma, obstructive jaundice, abnormal liver function.

The following patients are contraindicated to use this product: 1. Those who are allergic to progesterone or other ingredients in Qining Capsules (progesterone capsules); 2. Those with unexplained vaginal bleeding; 3. Those with thrombophlebitis, vascular embolism, cerebral stroke or a history of the disease; 4. Those with breast tumors or genital tumors.

Precautions for children: Data is still lacking. Precautions for pregnancy and lactation: This product has been found to have adverse effects on the fetus in animal experiments, but pregnant women can only use this product with the consent of a doctor. Progesterone is secreted into breast milk in trace amounts, but no adverse effects on infants have been found so far. Precautions for the elderly: Data is still lacking.

Phenobarbital, phenytoin sodium, rifampicin and other drugs can weaken the efficacy of this product due to their induction effect on cytochrome P450. Ketoconazole is an inhibitor of cytochrome P450 enzymes, so the inhibition of ketoconazole or other cytochrome enzymes may increase the blood concentration of progesterone.

[02] Cool storage area for medicines (below 20°C)

100 mg

24 months

Zhejiang Aisheng Pharmaceutical Co., Ltd.

• Founded in:

  1995-12-25

• Address:

  No. 8, Second Street, Hangzhou Economic and Technological Development Zone, Zhejiang Province

• Tax NO.:

  91330101609136936H

• Registered Funds:

  43.029824 yuan

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