Scopolamine Butylbromide

This product is an M cholinergic receptor blocker. Its peripheral effects are similar to those of atropine, with only a slight difference in the degree of action: this product has a stronger antispasmodic effect on smooth muscle than atropine, and can selectively relieve gastrointestinal, bile duct and urinary tract smooth muscle spasms and inhibit their peristalsis. It can also be used to relieve vascular smooth muscle spasms and improve microcirculation; its inhibitory effect on the secretion of glands such as the heart, eye smooth muscle (mydriasis and accommodation paralysis) and salivary glands is weaker than that of atropine. Its central effects mainly include: it has an excitatory effect on the respiratory center; its anti-vertigo and anti-tremor paralysis effects are stronger than atropine; but it has a significant sedative effect on the central nervous system, and a larger dose can produce a hypnotic effect. Therefore, the use of this product rarely causes side effects such as central nervous system excitement, mydriasis, and inhibition of saliva secretion similar to those caused by atropine.

1. Used for preoperative preparation of gastrointestinal endoscopic examination, endoscopic retrograde pancreaticocholangiopancreatography, and gas-barium hypotonic radiography or abdominal CT scan of the stomach, duodenum and colon, which can reduce or inhibit gastrointestinal motility; 2. Used for gastrointestinal spasm, biliary colic, renal colic or gastrointestinal hypermotility caused by various causes.

Intramuscular injection, intravenous injection or dissolved in 5% glucose injection or sodium chloride injection for intravenous drip. For adults, take 10-20 mg each time, or take 10 mg once, and then take another 10 mg after an interval of 20-30 minutes.

1. It is contraindicated for patients with severe heart disease, organic pyloric stenosis or paralytic intestinal obstruction; 2. It should be used with caution in patients with glaucoma and prostatic hypertrophy.

1. When used in combination with other anticholinergics, phenothiazines and other drugs, it will increase toxicity; 2. It can antagonize the gastrointestinal motility-promoting effects of metoclopramide, domperidone and the like; 3. Certain antiarrhythmic drugs (such as quinidine, disopyramide, etc.) should be used with caution in combination with this product, because the former have the effect of blocking the vagus nerve, so they can enhance the anticholinergic effect of this product, leading to dry mouth, blurred vision, and dysuria, and the elderly should pay special attention to this; 4. When this product is used in combination with adrenergic drugs (such as: dextroamphetamine 5mg), it can enhance the antiemetic effect and reduce the drowsiness of this product, but the dry mouth is more significant; 5. When used in combination with tricyclic antidepressants (amitriptyline, etc.), both have anticholinergic effects, and side effects such as dry mouth, constipation, and blurred vision are aggravated, which can cause urinary retention in elderly patients and induce

Keep away from light and store in sealed container.

Yantai Luyin Pharmaceutical Co., Ltd.

• Founded in:

  1993-12-20

• Address:

  No. 102, Baishi Road, Yantai City, Shandong Province

• Tax NO.:

  91370600613415452L

• Registered Funds:

  132.074 million yuan

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