Ethambutol Hydrochloride Tablets

This product is a synthetic antibacterial anti-tuberculosis drug. Its mechanism of action has not yet been fully elucidated. This product can penetrate into the mycobacteria to interfere with the synthesis of RNA, thereby inhibiting the reproduction of bacteria. This product is only effective against mycobacteria in the growth and reproduction period. So far, no cross-resistance has been found between this product and other anti-tuberculosis drugs.

Ethambutol hydrochloride

This product is white tablets

It is suitable for the treatment of pulmonary tuberculosis caused by Mycobacterium tuberculosis in combination with other anti-tuberculosis drugs. It can also be used to treat tuberculous meningitis and atypical mycobacterial infections.

1. Common dosage for adults: used in combination with other anti-tuberculosis drugs. For initial treatment of tuberculosis, take 15 mg/kg of body weight once a day; or take 25-30 mg/kg orally each time, up to 2.5 g, 3 times a week; or 50 mg/kg, up to 2.5 g, twice a week. For retreatment of tuberculosis, take 25 mg/kg of body weight once a day for 60 consecutive days, followed by 15 mg/kg of body weight once a day. For atypical mycobacterial infection, take 15-25 mg/kg of body weight once a day. 2. Common dosage for children: This product should not be used for children under 13 years old; the dosage for children over 13 years old is the same as that for adults.

1. The more common symptoms are blurred vision, eye pain, red-green color blindness or decreased vision, and narrowed visual field (optic neuritis is prone to occur when the daily dose is 25 mg/kg or more). Visual changes can be unilateral or bilateral; 2. The less common symptoms are chills, joint swelling and pain (especially the big toe, condyle, and knee joints), and a feeling of heat and tension on the surface of the affected joints (acute gout, hyperuricemia); 3. The rarest symptoms are allergic reactions such as rash, fever, and joint pain; or numbness, tingling, burning pain, or weakness in the hands and feet (peripheral neuritis).

It is contraindicated in patients who are allergic to azithromycin or any other macrolide drug.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Animal reproductive toxicity studies have shown that azithromycin crosses the placenta, but there is no sign of damage to the fetus. There is no data on the secretion of this product in breast milk. The safety of use in human pregnancy and lactation has not yet been confirmed, so this product should only be used when pregnant or lactating women have no appropriate choice. Precautions for the elderly: Not yet clear.

1. Combination with ethionamide may increase adverse reactions; 2. Combination with aluminum hydroxide may reduce the absorption of this product; 3. Combination with neurotoxic drugs may increase the neurotoxicity of this product, such as optic neuritis or peripheral neuritis.

Keep in a sealed container

0.25g

24 months

Sinopharm Zhijun (SHENZHEN) Pingshan Pharmaceutical Co., Ltd.

• Founded in:

  1990-07-13

• Address:

  No. 18, Qinglan 3rd Road, Pingshan New District, Shenzhen

• Tax NO.:

  91440300192194304B

• Registered Funds:

  50 million yuan

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