Roxithromycin Capsules

This product is a semi-synthetic 14-membered macrolide antibiotic. The antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. It is slightly less effective than erythromycin against Gram-positive bacteria, and stronger than erythromycin against Legionella pneumophila. The antimicrobial effect against Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin. This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor ("P" position), blocking the transfer RNA (t-RNA) binding to the "P" position, and also blocking the transfer of the polypeptide chain from the acceptor position ("A" position) to the "P" position, thereby inhibiting bacterial protein synthesis.

Roxithromycin

This product is in the form of capsules.

This product is suitable for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae; urethritis and cervicitis caused by Chlamydia trachomatis; skin and soft tissue infections caused by sensitive bacteria.

Take orally on an empty stomach. The general course of treatment is 5 to 12 days. Adults can take 150 mg twice a day or 300 mg once a day. Children can take 2.5 to 5 mg/kg twice a day.

The main adverse reactions are gastrointestinal reactions such as abdominal pain, diarrhea, nausea, and vomiting, but the incidence is significantly lower than that of erythromycin. Occasionally, there are rash, itchy skin, dizziness, headache, abnormal liver function (increased ALT and AST), and decreased peripheral blood cells.

Patients who are allergic to this product, erythromycin or other macrolide drugs are contraindicated.

Precautions for children: Not clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Less than 0.05% of the dose is excreted into breast milk. Although there are reports that it has little effect on infants, it is still necessary to consider whether to stop breastfeeding. Precautions for the elderly: If the pharmacokinetics in the elderly do not change significantly, there is no need to adjust the dose.

1. It is not compatible with ergotamine, dihydroergotamine, bromocriptine, terfenadine, ketoconazole and cisapride. 2. It has little effect on the metabolism of aminophylline and has little effect on carbamazepine, warfarin, ranitidine and other antacids.

Sealed, store in a dry place.

0.15g

24 months

Zhejiang Jingxin Pharmaceutical Co., Ltd.

• Founded in:

  1999-02-13

• Address:

  No. 800, Xinchang Avenue East Road, Yulin Street, Xinchang County, Zhejiang Province

• Tax NO.:

  91330000704503984N

• Registered Funds:

  861.02914 million yuan

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