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Clopidogrel Bisulfate Tablets

Function and Efficacy

This product is a platelet aggregation inhibitor that can selectively inhibit the binding of ADP to platelet receptors, and then inhibit the activation of ADP and glycoprotein GPⅡb/Ⅲa complex, thereby inhibiting platelet aggregation. This product can also inhibit platelet aggregation caused by non-ADP, and does not affect the activity of phosphodiesterase. This product affects the life of platelets by irreversibly changing platelet ADP receptors.

Ingredients

Clopidogrel bisulfate

Name Description Content CAS NO. Manufacturer
Clopidogrel hydrogen sulfateIngredients

This product is a platelet aggregation inhibitor that can selectively inhibit the binding of ADP to platelet receptors, and then inhibit the activation of ADP and glycoprotein GPⅡb/Ⅲa complex, thereby inhibiting platelet aggregation. This product can also inhibit platelet aggregation caused by non-ADP, and does not affect the activity of phosphodiesterase. This product affects the life of platelets by irreversibly changing platelet ADP receptors.

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135046-48-9 92

Appearance

This product is white or off-white tablets.

Indication

Prevent and treat circulatory disorders of the heart, brain and other arteries caused by high platelet aggregation.

Usage and Dosage

Oral administration, can be taken with or without food. Once a day, two tablets each time.

Adverse Reactions

Gastrointestinal reactions (such as abdominal pain, indigestion, constipation or diarrhea), rash, skin and mucous membrane bleeding, and rarely leukopenia and granulocytopenia may occur.

Precautions

1. It is contraindicated for patients who are allergic to the drug or any of its ingredients; 2. It is contraindicated for patients with severe liver damage; 3. It is contraindicated during pregnancy; 4. It is contraindicated for patients with active pathological bleeding, such as peptic ulcer or intracranial hemorrhage.

Special Population Medication

Precautions for children: Not clear. Precautions for pregnancy and lactation: Due to insufficient clinical research on pregnant and lactating women, it can only be used for pregnant women when necessary. Animal studies have shown that this product can enter breast milk, so the importance of the drug to lactating women should be considered when deciding whether to stop breastfeeding or stop taking the drug. Precautions for the elderly: Elderly patients do not need to adjust the dose when using this product.

Drug Interactions

1. Aspirin: This product increases the inhibitory effect of aspirin on platelet aggregation caused by collagen. There is no further research data on the safety of long-term combined use. 2. Heparin: Studies on healthy volunteers have shown that this product has no interaction with heparin. However, caution should be exercised when combined. 3. Nonsteroidal anti-inflammatory drugs (NSAIDs): When healthy volunteers take this product and naproxen at the same time, gastrointestinal occult blood loss increases. Therefore, caution should be exercised when this product is combined with NSAIDs. 4. Warfarin: There is no safety study on combined use.

Storage

Keep in a dark, sealed, cool and dry place (not exceeding 20℃).

Packaging Specification

25mg (calculated as C16H16ClNO2S)

Validity Period

36 months

Manufacturer

Germany Pharmaceutical Co., Ltd.

  • Founded in:

    2010-12-06
  • Address:

    No. 216, East Section of Ping'an Avenue, Xiangcheng City, Henan Province
  • Tax NO.:

    914116005664681555
  • Registered Funds:

    55 million yuan
  • Website:

  • Email:

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