(±)-Clopidogrel bisulfate
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(±)-Clopidogrel bisulfate
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CAS No:
135046-48-9
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Formula:
C16H16ClNO2S.H2O4S
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Chemical Name:
(±)-Clopidogrel bisulfate
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Synonyms:
Thieno[3,2-c]pyridine-5(4H)-acetic acid,α-(2-chlorophenyl)-6,7-dihydro-,methyl ester,sulfate (1:1);(±)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate hydrogen sulfate salt (1:1);(±)-Clopidogrel bisulfate;Methyl 2-(2-Chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate;(RS)-Clopidogrel bisulfate;(RS)-Clopidogrel bisulfate;140623-71-8
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CAS No:
Description
Colorless to light yellow liquiClopidogrel hydrogen sulfate is similar to ticlopidine, which is a new anti-platelet aggregation drug, successfully developed by French Sanofi-Synthelabo Fort for the prevention and treatment of heart, brain and other arterial circulation disorders caused by the high blood platelet aggregation, such as recent onset of stroke, myocardial infarction and patients diagnosed with peripheral arterial disease. Many countries have already used it, including United States,
Characteristics
140.76000
4.03980
white
184°C
423.7ºC at 760 mmHg
210ºC
DMSO: ~26mg/mL
2-8°C
2.9X10-7 mm Hg at 25 °C (est)
D20 +55.10° (c = 1.891 in methanol)
(±)-Clopidogrel bisulfate Use and Manufacturing
platelet aggregation inhibitors.Clopidogrel bisulfate is used in the synthesis of clopidogrel derivatives to be used as a platelet aggregation inhibitor. Antiplatelet aggregation drugs play a central role in the pathogenesis of acute thrombotic cardiovascular and cerebrovascular events caused by thrombosis caused by atherosclerotic plaque, and this role has been fully studied.
Computed Properties
Molecular Weight:419.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:419.0264073
Monoisotopic Mass:419.0264073
Topological Polar Surface Area:141
Heavy Atom Count:26
Complexity:463
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
No specific description provided
Registered Holders
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SIGNA SA DE CV
Active
United States
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Beijing Sinotau Intl. Pharmaceutical Technology Co., Ltd.
Active
China
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China Chinopharma Ltd
Active
China
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