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Haloperidol injection

Function and Efficacy

This product belongs to the butyrophenone antipsychotic drug. Its antipsychotic effect is related to its ability to block dopamine receptors in the brain and promote the conversion of dopamine in the brain. It has a good effect on resisting hallucinations and delusions and excitement and agitation, has a strong effect in blocking extrapyramidal dopamine, and also has a strong antiemetic effect, but its sedative and α-adrenaline receptor and cholinergic receptor blocking effects are weak.

Ingredients

The main ingredient of this product is haloperidol, and its chemical name is: 1-(4-fluorophenyl)-4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-butanone.

Name Description Content CAS NO. Manufacturer
HaloperidolIngredients

The antipsychotic effect is related to its ability to block dopamine receptors in the brain and promote the conversion of dopamine in the brain. It has a good effect on resisting hallucinations and delusions and excitement and agitation. It has a strong effect on blocking extrapyramidal dopamine and antiemetic effect, but its sedative effect and blocking α-adrenaline receptors and cholinergic receptors are weak.

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Appearance

This product is a sugar-coated tablet, which appears white after removing the sugar coating.

Indication

It is used for acute and chronic schizophrenia, mania, Tourette syndrome. It is effective in controlling excitement, agitation, hostility and aggressive behavior. Because this product has fewer adverse reactions to the cardiovascular system, it can also be used for organic brain disorders and senile mental disorders.

Usage and Dosage

For the treatment of schizophrenia, start with a small oral dose, 2-4 mg once, 2-3 times a day. Gradually increase to the usual dose of 10-40 mg per day, and the maintenance dose is 4-20 mg per day. For the treatment of Tourette syndrome, 1-2 mg once, 2-3 times a day.

Adverse Reactions

1 Extrapyramidal reactions are more severe and common. Acute dystonia is more likely to occur in children and adolescents, with obvious torsion spasms, dysphagia, akathisia and Parkinson's disease. 2 Long-term and excessive use may cause tardive dyskinesia. 3 Dry mouth, blurred vision, fatigue, constipation, sweating, etc. may occur. 4 It may cause an increase in plasma prolactin concentration, and possible related symptoms are: galactorrhea, gynecomastia, menstrual disorders, and amenorrhea. 5 A small number of patients may experience depressive reactions. 6 Allergic rashes, neutropenia and malignant syndrome are occasionally seen.

Precautions

Patients with basal ganglia lesions, Parkinson's disease, Parkinson's syndrome, severe central nervous system depression, bone marrow suppression, glaucoma, myasthenia gravis and allergic to this product.

Special Population Medication

Precautions for children: Use with caution. Precautions for pregnancy and lactation: Use with caution for pregnant women. Lactating women should stop breastfeeding while using this product. Precautions for the elderly: Use with caution and reduce the dosage as appropriate.

Drug Interactions

1 When this product is used in combination with ethanol or other central nervous system depressants, the central nervous system depressant effect is enhanced. 2 When this product is used in combination with amphetamine, the effect of the latter can be reduced. 3 When this product is used in combination with barbiturates or other anticonvulsants: it can change the form of epileptic seizures; it cannot enhance the efficacy of anticonvulsants. 4 When this product is used in combination with antihypertensive drugs, severe hypotension can occur. 5 When this product is used in combination with anticholinergic drugs, it may increase intraocular pressure. 6 When this product is used in combination with adrenaline, due to the blocking of α receptors, the activity of β receptors becomes dominant, which can lead to a decrease in blood pressure. 7 When this product is used in combination with lithium salts, attention should be paid

Storage

Keep away from light and store in sealed container.

Packaging Specification

1ml:5mg

Validity Period

36 months

Manufacturer

Shanghai Xudong Haipu Pharmaceutical Co., Ltd.

  • Founded in:

    1993-01-06
  • Address:

    No. 879, Jinhu Road, China (Shanghai) Pilot Free Trade Zone
  • Tax NO.:

    91310115607203592Y
  • Registered Funds:

    $9,478,623
  • Website:

  • Email:

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