On ECHEMI
Home > Drugs > Terfenadine Granules

Terfenadine Granules

Function and Efficacy

Specific H1 receptor blocker. At effective antihistamine doses, this product and its metabolites are not easy to pass through the blood-brain barrier, so there is little central nervous system inhibitory effect.

Ingredients

The main ingredient of this product and its chemical name is terfenadine, and its chemical name is α-(p-tert-butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinol.

Name Description Content CAS NO. Manufacturer
TerfenadineIngredients

Specific H1 receptor blocker. At effective antihistamine doses, this product and its metabolites are not easy to pass through the blood-brain barrier, so there is little central nervous system inhibitory effect.

More
50679-08-8 18

Appearance

White, off-white or slightly yellow suspension granules with sweet taste.

Indication

1. Seasonal allergic rhinitis, perennial allergic rhinitis. 2. Acute and chronic urticaria, etc.

Usage and Dosage

Oral: Adults and patients under 12 years old, 60 mg once, twice a day; children 6 to 12 years old, 30 mg once, twice a day, or as directed by a doctor.

Adverse Reactions

1. Cardiovascular system: Severe adverse reactions rarely occur: such as ventricular tachyarrhythmia, hypotension, syncope, prolonged QT interval, and even cardiac arrest and death. According to foreign literature reports, the following adverse reactions are rare. Such as: ventricular arrhythmia, torsades de pointes, ventricular tachycardia, ventricular fibrillation, cardiac arrest, hypotension, atrial flutter, syncope, dizziness, prolonged QTc period, etc. Most of the above reactions are caused by drug interactions. 2. Central nervous system: such as drowsiness, headache, fatigue, dizziness, nervousness, weakness, etc. 3. Gastrointestinal system: such as stomach discomfort, nausea, vomiting, increased appetite, and changes in bowel habits.

Precautions

1. Patients who are allergic to this product are prohibited from using it. 2. It is contraindicated to use it in combination with triazole antifungal drugs (such as ketoconazole, itraconazole, etc.), certain macrolide antibiotics (such as clarithromycin, erythromycin, oleandomycin, etc.) and other drugs that seriously damage liver function. 3. Patients with obvious liver damage are prohibited from using it. 4. Patients with organic heart disease are prohibited from using it, especially those with atrioventricular conduction block and congenital long QT syndrome. 5. It is contraindicated to take it in excess.

Drug Interactions

It is contraindicated to be used in combination with certain azole antifungal drugs (such as ketoconazole, itraconazole, etc.), certain macrolide antibiotics (such as clarithromycin, erythromycin, oleandomycin, etc.) and other drugs that seriously damage liver function.

Storage

Keep in a light-proof, sealed, dry place.

Packaging Specification

30mg

Manufacturer

Jiangsu Fubang Pharmaceutical Co., Ltd.

  • Founded in:

    2000-06-16
  • Address:

    No. 18, Shenzhen Road, Guannan Economic Development Zone, Guannan County, Jiangsu
  • Tax NO.:

    91320724703814588M
  • Registered Funds:

    5 million yuan
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.