On ECHEMI
Home > Drugs > Amoxicillin Capsules

Amoxicillin Capsules

Function and Efficacy

This product is a penicillin antibiotic, which has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococcus and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

Ingredients

The main ingredient of this product is amoxicillin, and its chemical name is: (2S,5R,6R)-3,3-dimethyl-6-[(R)-(-)-2-amino-2-(4-hydroxyphenyl)acetylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate.

Name Description Content CAS NO. Manufacturer
AmoxicillinIngredients

This product is a penicillin antibiotic, which has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococcus and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.

More
26787-78-0 30

Appearance

This product is in the form of capsules.

Indication

1. Otitis media, sinusitis, pharyngitis, tonsillitis and other upper respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 2. Urogenital tract infections caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis. 3. Skin and soft tissue infections caused by hemolytic streptococci, staphylococcus or Escherichia coli. 4. Acute bronchitis, pneumonia and other lower respiratory tract infections caused by hemolytic streptococci, pneumococcus, staphylococcus or Haemophilus influenzae. 5. Acute simple gonorrhea. 6. This product can also be used to treat typhoid fever, typhoid carriers and leptospirosis; amoxicillin can also be used in combination with clarithromycin and lansoprazole to eradicate gastric and duodenal Helicobacter pylori and reduce the recurrence rate of peptic ulcers.

Usage and Dosage

oral. Adults take 0.5g once every 6 to 8 hours, and the daily dose should not exceed 4g. The daily dose for children is 20-40 mg/Kg, once every 8 hours; for infants under 3 months old, the daily dose is 30 mg/Kg, once every 12 hours. Patients with severe renal impairment need to adjust the dosage, including 0.25-0.5g every 12 hours for patients with endogenous creatinine clearance 10-30ml/min; 0.25-0.5g every 24 hours for patients with endogenous creatinine clearance less than 10ml/min.

Adverse Reactions

1 Gastrointestinal reactions such as nausea, vomiting, diarrhea and pseudomembranous colitis. 2 Allergic reactions such as rash, drug fever and asthma. 3 Anemia, thrombocytopenia, eosinophilia, etc. 4 Serum aminotransferase may be slightly elevated. 5 Superinfection caused by Candida or drug-resistant bacteria. 6 Occasionally, central nervous system symptoms such as excitement, anxiety, insomnia, dizziness and abnormal behavior may occur.

Precautions

It is contraindicated in patients with penicillin allergy or penicillin skin test positive.

Special Population Medication

Precautions for children: 1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but their clinical significance is unclear. Precautions for pregnancy and lactation: Animal reproduction studies have shown that amoxicillin at 10 times the human dose did not damage the fertility and fetus of rats and mice. However, there is still a lack of sufficient controlled studies in humans. Given that animal reproduction studies cannot fully predict human reactions, pregnant women should only use this product when it is really necessary. Since a small amount of amoxicillin can be secreted in breast milk, it may cause allergies in infants after being taken by nursing mothers. Precautions for the elderly: This product has not been tested and there are no reliable references.

Drug Interactions

1. Probenecid competitively reduces the renal tubular secretion of this product. The simultaneous use of the two can cause an increase in the blood concentration of amoxicillin and a prolonged half-life. 2. Chloramphenicol, macrolides, sulfonamides and tetracyclines interfere with the antibacterial effect of amoxicillin in vitro, but the clinical significance is unclear.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.25g

Validity Period

36 months

Manufacturer

Jilin Jinnuo Pharmaceutical Co., Ltd.

  • Founded in:

    2010-05-14
  • Address:

    No. 999-B, Xingfu East Road, Zhenlai Economic Development Zone, Jilin Province
  • Tax NO.:

    912208215552624425
  • Registered Funds:

    5 million yuan
  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.