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Secnidazole tablets

Function and Efficacy

Secnidazole enters the microorganism by passive diffusion, and destroys the DNA of microorganisms and anaerobic cells through the reduction of 5-nitroimidazole. The mechanism of action is similar to other 5-nitroimidazole drugs. Pharmacodynamic studies have shown that secnidazole has extremely strong selective toxicity to Trichomonas protozoa and anaerobic microorganisms. Toxicological effects: Animal experiments have not shown that this product has teratogenic effects, but like other 5-nitroimidazole drugs, this product should be avoided as much as possible in the first three months of pregnancy.

Ingredients

The main ingredient is: Secnidazole. The chemical name is: 1-(2-hydroxypropyl)-2-methyl-5-nitroimidazole hemihydrate.

Name Description Content CAS NO. Manufacturer
alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanolIngredients

It destroys the DNA of microorganisms and anaerobic bacteria cells through the reduction of 5-nitroimidazole, and has strong selective toxicity to Trichomonas protozoa and anaerobic microorganisms.

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3366-95-8 11

Indication

This product is suitable for benign memory disorders, improving patients' ability of directed memory, associative learning, image recall, meaningless pattern recognition and portrait recall. It also improves memory disorders caused by dementia patients and organic brain lesions. In addition, this product is also used to treat myasthenia gravis.

Usage and Dosage

Usage: Oral, before meals. Dosage: 1 Urethritis and vaginitis caused by Trichomonas vaginalis: Adults, 2g, single dose. Spouses should take it at the same time. 2 Intestinal amoebiasis Symptomatic acute amoebiasis: Adults: 2g, single dose; Children: 30mg/kg, single dose. Asymptomatic acute amoebiasis: Adults: 2g once, once a day, for 3 consecutive days; Children: 30mg/kg once, once a day, for 3 consecutive days. 3 Hepatic amoebiasis: Adults: 1.5g per day, orally once or in divided doses, for 5 consecutive days; Children: 30mg/kg once, orally once or in divided doses, for 5 consecutive days. 4 Giardiasis: Children, 30mg/kg, single dose.

Adverse Reactions

Common adverse reactions include metallic taste in the mouth. Occasional adverse reactions include digestive tract disturbances (such as nausea, vomiting, diarrhea, abdominal pain), skin allergic reactions (such as rash, urticaria, itching), dark urine, and leukopenia (return to normal after discontinuation of the drug). Rare adverse reactions include dizziness, headache, and moderate neurological dysfunction.

Precautions

The following patients are contraindicated: 1. Those who are allergic to secnidazole or general nitroimidazole drugs; 2. Pregnant and lactating women.

Drug Interactions

1. This product can cause delirium or mental disorder when taken together with disulfiram (also known as anabolic sulfamethoxazole). Do not drink alcohol during treatment with this product or at least within one day after taking the medicine to avoid disulfiram-like reactions. 2. This product has a strong inhibitory effect on the anticoagulant effect of warfarin, so patients with a history of abnormal blood counts should not take it.

Storage

Keep in a sealed container

Packaging Specification

0.25g

Manufacturer

Hunan Jiudian Pharmaceutical Co., Ltd.

  • Founded in:

    2001-01-19
  • Address:

    No. 1 Jiankang Avenue, Liuyang Economic and Technological Development Zone, Changsha
  • Tax NO.:

    91430100722520761D
  • Registered Funds:

    345.145427 yuan
  • Website:

  • Email:

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