Loratadine Tablets

Pharmacology: This product is a long-acting tricyclic antihistamine that competitively inhibits histamine H1 receptors and inhibits allergic symptoms caused by histamine. This product has no obvious anticholinergic and central nervous system inhibitory effects. Toxicology: No obvious teratogenic effects were found in animal tests.

The main ingredient of this product and its chemical name are: 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cycloheptyl[1,2-b]pyridine-11-ylidene)-1-piperidinecarboxylic acid ethyl ester.

This product is a white tablet.

It is used to relieve symptoms associated with allergic rhinitis, such as sneezing, runny nose, itchy nose, nasal congestion, and itchy and burning eyes. After oral administration, nasal and eye symptoms and signs are quickly relieved. It is also suitable for relieving symptoms and signs of chronic urticaria, itchy skin diseases and other allergic skin diseases.

Take on an empty stomach. Adults and children over 12 years old take 10 mg each time, once a day.

At the recommended dose of 10 mg per day, this product has no obvious sedative effect. Common adverse reactions include fatigue, headache, drowsiness, dry mouth, gastrointestinal discomfort including nausea, gastritis and rash. Rare adverse reactions include hair loss, allergic reactions, abnormal liver function, tachycardia and palpitations.

It is contraindicated for patients who are allergic to this product or have special physical conditions.

Precautions for children: The safety of this product for children under 12 years old has not been determined. Precautions for pregnancy and lactation: Pregnant women should use with caution. Breastfeeding should be stopped during medication. Precautions for the elderly: Mild to moderate impairment of liver and kidney function has no significant effect on the metabolism and excretion of this drug, so the dosage for elderly patients is the same as that for adults.

Drugs that inhibit the function of liver drug metabolizing enzymes can slow down the metabolism of this product. Taking ketoconazole 400 mg daily can increase the plasma concentration of loratadine and its active metabolite descarboxyethyl loratadine, but no electrocardiogram changes were observed. Combination use with macrolide antibiotics, cimetidine, theophylline and other drugs can also inhibit the metabolism of loratadine.

Store at room temperature, away from light, in an airtight container.

10mg

30 months

Henan Jiushi Pharmaceutical Co., Ltd.

• Founded in:

  2002-06-24

• Address:

  Southeast of Zhoubu Village, Huixian City

• Tax NO.:

  91410700173249269M

• Registered Funds:

  48 million yuan

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