Fluphenazine Hydrochloride Tablets

This product belongs to the piperazine phenothiazine. Its antipsychotic effect is mainly related to its blocking of dopamine receptors (DA11) in the brain, inhibiting the ascending activation system of the reticular formation and having a sedative effect. Its antiemetic and blood pressure lowering effects are weaker.

The main ingredient of this product is fluphenazine hydrochloride, and its chemical name is: 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride.

This product is a sugar-coated tablet, which appears white after removing the sugar coating.

It is used for various types of schizophrenia, has an uplifting and activating effect, and is suitable for symptoms such as emotional indifference and behavioral withdrawal in simple, catatonic and chronic schizophrenia.

Start with a small oral dose, 2 mg each time, 2 to 3 times a day, and gradually increase to 10 to 20 mg a day, with the highest dose not exceeding 30 mg a day.

Extrapyramidal reactions are common, such as akathisia, acute dystonia and Parkinson's disease. Long-term and excessive use may cause tardive dyskinesia. Palpitations, insomnia, fatigue, dry mouth, blurred vision, dysuria, constipation, galactorrhea, gynecomastia, menstrual disorders, amenorrhea, etc. may occur. Rarely, drowsiness, restlessness, dizziness, and urinary retention are seen. Allergic rash, leukopenia and malignant syndrome are occasionally seen. Occasionally, it may cause postural hypotension, palpitations or electrocardiogram changes, toxic liver damage or obstructive jaundice, bone marrow suppression, and epilepsy.

Patients with basal ganglia lesions, Parkinson's disease, Parkinson's syndrome, bone marrow suppression, glaucoma, coma and allergy to phenothiazines.

Precautions for children: Children under 6 years old are prohibited to use. Children over 6 years old should reduce the dosage as appropriate. Precautions for pregnancy and lactation: Pregnant women should use with caution. Lactating women should stop breastfeeding while using this product. Precautions for the elderly: Start with a small dose. Reduce the dosage as appropriate depending on the condition to reduce the occurrence of extrapyramidal reactions and tardive dyskinesia.

1. When this product is used in combination with ethanol or other central nervous system depressants, the central nervous system depressant effect is enhanced. 2. When this product is used in combination with antihypertensive drugs, it is easy to cause the risk of postural hypotension. 3. When this product is used in combination with sultopride, there is a risk of ventricular arrhythmia, which may cause torsades de pointes in severe cases. 4. When this product is used in combination with atropine drugs, adverse reactions are aggravated. 5. When this product is used in combination with lithium salts, it may cause loss of consciousness.

Keep away from light and store in sealed container.

2mg

24 months

Henan Jiushi Pharmaceutical Co., Ltd.

• Founded in:

  2002-06-24

• Address:

  Southeast of Zhoubu Village, Huixian City

• Tax NO.:

  91410700173249269M

• Registered Funds:

  48 million yuan

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