Pimidic Acid Capsules

This product is a quinolone antibacterial drug, which has antibacterial effects on Gram-negative bacteria, such as Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Serratia, Salmonella typhi, Shigella, Pseudomonas aeruginosa, etc. This product acts on bacterial DNA gyrase, interfering with the synthesis of bacterial DNA, thereby causing bacterial death.

The main component of this product is pipemidic acid; its chemical name is: 8-ethyl-5-oxo-5,8-dihydro-2-(1-piperazinyl)pyrido[2,3-d]pyrimidine-6-carboxylic acid trihydrate. Molecular formula: C14H17N5O33H2O Molecular weight: 357.37

This product is in the form of capsules.

Used for acute and chronic otitis media caused by sensitive bacteria.

Adults take 0.5g orally at a time and 1 to 2g per day.

After the product is absorbed from the wound surface, its adverse reactions are mainly gastrointestinal reactions such as nausea, belching, upper abdominal discomfort, loss of appetite, loose stools or constipation, and skin rash or systemic itching are rare; dizziness, headache, transient increase in serum aminotransferase, etc. are occasionally seen. The above adverse reactions are all mild and can be recovered by themselves after stopping the drug.

Patients who are allergic to this product and quinolones are contraindicated.

Precautions for children: The safety of this product in infants and adolescents under 18 years of age has not been established. However, this product can cause joint lesions when used in several young animals. Therefore, it is not suitable for children and adolescents under 18 years of age. Precautions for pregnancy and lactation: Animal experiments show that this product can inhibit the development of cartilage in young animals. Pregnant women and lactating women should not use it. Precautions for the elderly: The dosage of elderly patients should be adjusted according to their renal function.

1. Probenecid can inhibit the renal tubular secretion of this product after absorption from the wound surface. When used together, the latter's blood concentration increases and the half-life (t1/2) is prolonged. 2. This product can reduce the clearance of caffeine from the liver, prolonging the latter's half-life (t1/2). Avoid using it together, or monitor the blood concentration of caffeine. 3. This product can significantly reduce the clearance of theophylline, causing the latter's blood concentration to increase, which is prone to toxic reactions. The two should not be used together. If they need to be used together, theophylline concentration should be monitored and the dosage should be adjusted. 4. It often has a synergistic effect with gentamicin, carbenicillin, penicillin, etc.

Keep sealed.

0.25g

24 months

Fujian Quanzhou Straits Pharmaceutical Co., Ltd.

• Founded in:

  2000-08-02

• Address:

  Room 911, Building 5, Sunshine International Plaza, No. 27, Antai Road, Luojiang District, Quanzhou City, Fujian Province

• Tax NO.:

  91350500717351959W

• Registered Funds:

  $6 million

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