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Nikethamide Injection

Function and Efficacy

This product selectively excites the medullary respiratory center, and can also act on the carotid body and aortic body chemoreceptors to reflexively excite the respiratory center, and increase the respiratory center's sensitivity to carbon dioxide, deepening and accelerating breathing. It has a weak excitatory effect on the vasomotor center. Excessive dosage can cause convulsions.

Ingredients

The main ingredient of this product is nikethamide, and its chemical name is: N,N-diethyl-3-pyridinecarboxamide.

Name Description Content CAS NO. Manufacturer
N,N-DIETHYLNICOTINAMIDEIngredients

It selectively excites the medullary respiratory center and can also act on the carotid body and aortic body chemoreceptors to reflexively excite the respiratory center and increase the respiratory center's sensitivity to carbon dioxide, deepening and accelerating breathing. It has a weak excitatory effect on the vasomotor center. Excessive doses can cause convulsions.

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Appearance

This product is a colorless clear liquid.

Indication

Used for central respiratory depression and respiratory depression caused by various reasons.

Usage and Dosage

The usual dosage for subcutaneous injection, intramuscular injection, and intravenous injection in adults is 0.25-0.5 g per time, and the dosage can be repeated every 1-2 hours if necessary. The maximum dosage is 1.25 g per time. The usual dosage for children under 6 months old is 75 mg per time, 0.125 g per time for 1 year old, and 0.175 g per time for 4-7 years old.

Adverse Reactions

Common symptoms include facial irritation, restlessness, convulsions, nausea and vomiting. High doses may cause increased blood pressure, palpitations, sweating, facial flushing, vomiting, tremors, arrhythmias, convulsions, and even coma.

Precautions

Patients with convulsions and seizures.

Drug Interactions

When used in combination with other central nervous system stimulants, it has a synergistic effect and can cause convulsions.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

1.5ml:0.375g

Manufacturer

Anhui Changjiang Pharmaceutical Co., Ltd.

  • Founded in:

    2001-12-25
  • Address:

    No. 152, Changjiang South Road, High-tech Industrial Development Zone, Wuhu City, Anhui Province (declaration commitment)
  • Tax NO.:

    91340200733036887Q
  • Registered Funds:

    82.35294118 million yuan
  • Website:

  • Email:

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