Adenosine triphosphate disodium-magnesium chloride injection

This product can penetrate the cell membranes of various important organs and increase the ATP level in tissues and cells. It can directly supply energy to cells under ischemic and hypoxic conditions, thereby improving cell energy, metabolism and cell membrane sodium pump mechanism, reducing cell swelling, improving microcirculatory disorders, and restoring organ function. This product can enter the mitochondria of ischemic and hypoxic myocardial cells, support cell energy supply, improve the imbalance of sodium, potassium, and magnesium inside and outside the cells, and inhibit the accumulation of Ca2 in cells. This product has a certain effect of scavenging oxygen free radicals, protecting cells, and promoting functional recovery.

This product is a sterile aqueous solution of adenosine triphosphate disodium (Solution A) and a sterile aqueous solution of magnesium chloride (Solution M) prepared separately and sealed separately. Solution A: 100 mg of adenosine triphosphate disodium per 2 ml; Solution M: 32 mg of magnesium chloride per 2 ml.

Liquid A is a colorless or almost colorless clear liquid; Liquid M is a colorless clear liquid.

This product is an auxiliary drug. It is used for the auxiliary treatment of acute and chronic active hepatitis, sequelae of ischemic cerebrovascular disease, brain damage, myocarditis and other diseases.

Intravenous drip. First, inject the A solution of this product into 250~500ml of 5% glucose injection, mix well, then add an equal volume of M solution of this product and mix well. The initial drip rate is controlled within 20 drops per minute. If there is no abnormality after 5 minutes, it is controlled within 50 drops per minute. Once a day, a single dose of 5mg/kg. 1~2 bottles of A solution at a time, plus 1~2 bottles of M solution, or follow the doctor's advice

Too fast an intravenous drip can have a hypotensive effect, causing chest tightness and a burning sensation throughout the body. Stopping the medication or slowing down the drip rate can restore blood pressure to normal levels.

1. Patients who are allergic to this product are prohibited from using this product. 2. Patients with new myocardial infarction and cerebral hemorrhage are prohibited from using this product.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

No pharmacokinetic interaction between this product and ribavirin was found in multiple-dose pharmacokinetic studies. The results of the pharmacokinetic interaction study of a single dose of this product showed that it had no effect on the activity of cytochrome P450CYP1A2, CYP2C8/9, CYP2D6, liver CYP3A4 or N-acetyltransferase. In addition, there are literature reports that when CYP1A2 substrates (such as theophylline) are used with other interferons, clearance is reduced by 50%. Therefore, care should be taken when this product is used with drugs that are metabolized by CYP1A2.

Sealed and stored in a cool dark place. Valid for 18 months.

A solution 2ml: 100mg; M solution 2ml: 32mg

18 months

Wuzhi Tongkang Pharmaceutical Co., Ltd.

• Founded in:

  2016-09-13

• Address:

  No. 331, Xingye Road, Wuzhi County Industrial Cluster Area

• Tax NO.:

  91230199MA1900TB1J

• Registered Funds:

  9.47 million yuan

• Email:

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