Ribavirin Tablets

It is a strong inhibitor of inosine monophosphate (IMP) dehydrogenase, which inhibits IMP and thus hinders the synthesis of viral nucleic acid. It has broad-spectrum antiviral properties and has inhibitory effects on a variety of viruses such as respiratory syncytial virus, influenza virus, herpes simplex virus, etc.

The main ingredient of this product is ribavirin, and its chemical name is 1--D-furanosyl-1H-1,2,4-triazole-3-carboxamide. Molecular formula: C8H12N4O5 Molecular weight: 244.21

This product is white tablets.

It has preventive and therapeutic effects on influenza (caused by influenza viruses A and B), adenovirus pneumonia, hepatitis A, herpes, measles, etc.

Oral administration, 0.8-1 g/day, divided into 3-4 doses.

① After systemic administration: digestive tract dysfunction, central nervous system disorder, anemia and reticulocytosis, increased serum bilirubin. ② High-dose use can cause heart damage, and can cause dyspnea, chest pain, etc. in patients with respiratory diseases (chronic obstructive pulmonary disease or asthma).

This medicine should not be used by women who are pregnant or may become pregnant.

Precautions for children: The oral dose for children under 6 years old has not been determined. Precautions for pregnancy and lactation: 1. This product has a strong teratogenic effect. A daily dose of 1 mg/kg in rabbits can cause embryo damage, so it is contraindicated for pregnant women and women who may become pregnant (this product is eliminated very slowly in the body and cannot be completely eliminated from the body 4 weeks after stopping the drug). 2. A small amount of the drug is excreted through breast milk and is toxic to both mother and offspring. Therefore, breastfeeding women should stop breastfeeding during medication and their breast milk should be discarded. Since respiratory syncytial virus infection in lactating women is self-limiting, this product is not used in such cases. Precautions for the elderly: It is not recommended for the elderly.

This product has an antagonistic effect when used together with zidovudine, because this product can inhibit the conversion of zidovudine into active zidovudine phosphate.

Keep away from light and store in sealed container.

0.1 g

24 months