Ribavirin Tablets
Function and Efficacy
1. Pharmacology: Broad-spectrum antiviral drug. It has the effect of inhibiting the growth of multiple viruses such as respiratory syncytial virus, influenza virus, hepatitis A virus, adenovirus, etc. in vitro, and its mechanism is not fully understood. This product does not change the adsorption, invasion and uncoating of viruses, nor does it induce the production of interferon. After entering the virus-infected cells, the drug is rapidly phosphorylated, and its product acts as a competitive inhibitor of viral synthase, inhibiting inosine monophosphate dehydrogenase, influenza virus RNA polymerase and mRNA guanosine transferase, thereby causing a decrease in intracellular guanosine triphosphate, impairing viral RNA and protein synthesis, and inhibiting viral replication and transmission. It may also have an immune effect and neutralizing antibody effect on respiratory syncytial virus.
Ingredients
Main ingredient: Ribavirin
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| RibavirinIngredients |
Broad-spectrum antiviral drug. It has the effect of inhibiting the growth of multiple viruses such as respiratory syncytial virus, influenza virus, hepatitis A virus, adenovirus, etc. in vitro, and its mechanism is not fully understood. After entering the virus-infected cells, the drug is rapidly phosphorylated, and its product acts as a competitive inhibitor of viral synthase, inhibiting inosine monophosphate dehydrogenase, influenza virus RNA polymerase and mRNA guanosine transferase, thereby causing a decrease in intracellular guanosine triphosphate, impairing viral RNA and protein synthesis, and inhibiting viral replication and transmission. It may also have an immune effect and neutralizing antibody effect on respiratory syncytial virus. More |
36791-04-5 | 33 |
Appearance
This product is white tablets
Indication
Suitable for viral pneumonia and bronchitis caused by respiratory syncytial virus, and skin herpes virus infection
Usage and Dosage
Oral. 1 Viral respiratory tract infection: Adults take 0.15g once, 3 times a day, for 7 days. 2 Skin herpes virus infection: Adults take 0.3g once, 3 times a day, for 7 days. 3 Children take 10mg/kg per day, divided into 4 doses, for 7 days.
Adverse Reactions
Common adverse reactions include anemia and fatigue, which disappear after stopping the drug. Less common adverse reactions include fatigue, headache, insomnia, loss of appetite, nausea, vomiting, mild diarrhea, constipation, etc., and can cause a decrease in red blood cells, white blood cells and hemoglobin.
Precautions
People who are allergic to this product and pregnant women are prohibited from using it
Special Population Medication
Precautions for children: The oral dose for children under 6 years old has not been determined. Precautions for pregnancy and lactation: 1. This product has a strong teratogenic effect. A daily dose of 1 mg/kg in rabbits can cause embryo damage, so it is contraindicated for pregnant women and women who may become pregnant (this product is eliminated very slowly in the body and cannot be completely eliminated from the body 4 weeks after stopping the drug). 2. A small amount of the drug is excreted through breast milk and is toxic to both mother and offspring. Therefore, breastfeeding women should stop breastfeeding during medication and their breast milk should be discarded. Since respiratory syncytial virus infection in lactating women is self-limiting, this product is not used in such cases. Precautions for the elderly: It is not recommended for the elderly.
Drug Interactions
This product has an antagonistic effect when used together with zidovudine, because this product can inhibit the conversion of zidovudine into active zidovudine phosphate.
Storage
Keep in a sealed container
Packaging Specification
100 mg
Validity Period
24 months
Manufacturer
Jiangxi Nanchang Jisheng Pharmaceutical Co., Ltd.
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Founded in:
1986-09-29 -
Address:
No. 666, Shizhen South Avenue, Traditional Chinese Medicine Science and Technology Innovation City, Ganjiang New District, Jiangxi Province -
Tax NO.:
91360127158261497H -
Registered Funds:
122.45 million yuan -
Website:
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Email: