Alfacalcidol Soft Capsules

1. Increase the reabsorption of calcium by the small intestine and renal tubules, inhibit parathyroid hyperplasia, reduce the synthesis and release of parathyroid hormone, and inhibit bone resorption. 2. Increase the synthesis of transforming growth factor-β (TGF-β) and insulin-like growth factor-I (IGF-I), and promote the synthesis of collagen and bone matrix protein. 3. Regulate muscle calcium metabolism, promote muscle cell differentiation, enhance muscle strength, increase neuromuscular coordination, and reduce the tendency to fall.

The main ingredient of this product is: Alfacalcidol.

This product is a red transparent capsule containing light yellow or yellow oily liquid.

1. Rickets and osteomalacia. 2. Renal osteodystrophy. 3. Osteoporosis. 4. Hypoparathyroidism.

Oral: Adults, chronic renal insufficiency and osteoporosis: 0.5 mu g (2 capsules) each time, once a day, or as directed by a doctor. Children should follow the doctor's advice.

Small doses alone (<1.0 μg/d) generally have no adverse reactions, but long-term high-dose use or combined use with calcium supplements may cause hypercalcemia and hypercalciuria.

It is contraindicated for patients who are allergic to vitamin D and its analogs, have hypercalcemia, or have signs of vitamin D poisoning.

Precautions for children: When giving this product to children, the serum calcium value and the calcium/chromium ratio in urine should be fully observed. At the same time, the dosage should be carefully controlled and gradually increased from a small amount to avoid overdose. Precautions for pregnancy and lactation: The safety of the drug for pregnant and lactating women has not yet been established. Precautions for the elderly: Generally speaking, due to the low physiological function of the elderly, the dosage should be taken with caution.

1 Calcium agents: Combination with calcium agents may cause elevated blood calcium, so blood calcium should be monitored. 2 Thiazide diuretics: This type of diuretic can promote the kidney's absorption of calcium, and there is a risk of hypercalcemia when used together. 3 Digitalis glycosides: Hypercalcemia in patients taking digitalis drugs can easily induce arrhythmias. If this drug is used in combination, blood calcium should be closely monitored. 4 Barbiturates, anticonvulsants: These drugs can accelerate the metabolism of active vitamin D metabolites in the liver and reduce the efficacy of the drug, so the dose of this drug should be appropriately increased. 5 Gastrointestinal absorption inhibitors: Cholestyramine or aluminum-containing antacids can reduce the absorption of this drug. The two should not be taken at the same time, and should be taken 2 hours apart.

Sealed and stored in a cool place.

0.5 μg

36 months

Shanghai Sine Yanan Pharmaceutical Co., Ltd.

• Founded in:

  2003-08-06

• Address:

  No. 298, Xinggong Road, Tinglin Town, Jinshan District, Shanghai

• Tax NO.:

  91310116753162119M

• Registered Funds:

  6.46 million yuan

• Email:

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