On ECHEMI
Home > Drugs > Vitamin D2 soft capsules

Vitamin D2 soft capsules

Function and Efficacy

This product is a vitamin drug. Vitamin D2 promotes the absorption of calcium by the brush border of the small intestinal mucosa and the reabsorption of phosphorus by the renal tubules, increases the concentration of blood calcium and phosphorus, cooperates with parathyroid hormone and calcitonin, promotes the release of calcium phosphate from old bones, and maintains and regulates the normal concentration of plasma calcium and phosphorus. Vitamin D2 promotes the deposition of calcium in the new bone formation site, deposits citrate in the bone, promotes bone calcification and the maturation of osteoblast function and bone-like tissue. After vitamin D2 is ingested, it is catalyzed by the 25-hydroxylase system in the cell microsomes to generate calcidiol (25-OHD3), which is catalyzed by the 1-hydroxylase system of the renal proximal tubular cells to generate biologically active calcitriol [1-25-(OH)2D3].

Ingredients

The main ingredient of this product is vitamin D2, and its chemical name is 9,10-secoergoster-5,7,10(19),22-tetraen-3β-ol.

Name Description Content CAS NO. Manufacturer
Vitamin D2Ingredients

Vitamin D2 promotes the absorption of calcium by the brush border of the small intestinal mucosa and the reabsorption of phosphorus by the renal tubules, increases the concentration of blood calcium and phosphorus, cooperates with parathyroid hormone and calcitonin, promotes the release of calcium phosphate from old bones, and maintains and regulates the normal concentration of plasma calcium and phosphorus. Vitamin D2 promotes the deposition of calcium in new bone formation sites, deposits citrate in bones, promotes bone calcification and the maturation of osteoblast function and bone-like tissue. After vitamin D2 is ingested, it is catalyzed by the 25-hydroxylase system in the cell microsomes to produce calcidiol (25-OHD3), which is catalyzed by the 1-hydroxylase system of the renal proximal tubular cells to produce biologically active calcitriol [1-25-(OH)2D3].

More
50-14-6 13

Appearance

This product is a capsule containing yellow or light yellow oily liquid.

Indication

1. For the prevention and treatment of vitamin D deficiency. Such as: absolute vegetarians, patients with parenteral nutrition, pancreatic insufficiency with malabsorption syndrome, hepatobiliary diseases (liver damage, cirrhosis, obstructive jaundice), small intestinal diseases (fatty diarrhea, localized enteritis, long-term diarrhea), gastrectomy, etc. 2. For the treatment of chronic hypocalcemia, hypophosphatemia, rickets, osteomalacia with chronic renal insufficiency, familial hypophosphatemia and hypoparathyroidism (postoperative, idiopathic or pseudohypoparathyroidism). 3. For the treatment of acute, chronic and potential postoperative tetany and idiopathic tetany.

Usage and Dosage

1 Prevention of vitamin D deficiency: Adults should take 0.01-0.02 mg (400-800 units) orally daily; premature infants, twins or formula-fed infants whose daily dietary vitamin D intake is less than 0.0025 mg (100 units) should take 0.0125-0.025 mg (500-1000 units) of vitamin D orally daily starting from 1 to 3 weeks after birth; breast-fed infants should take 0.01 mg (400 units) daily. 2 Vitamin D deficiency: Adults should take 0.025-0.05 mg (1000-2000 units) orally daily, and then reduce to 0.01 mg (400 units) daily; children should take 0.025-0.1 mg (1000-4000 units) daily.

Adverse Reactions

1. Constipation, diarrhea, persistent headache, loss of appetite, metallic taste in the mouth, nausea and vomiting, thirst, fatigue, and weakness; 2. Bone pain, cloudy urine, convulsions, hypertension, increased eye sensitivity to light stimulation, arrhythmia, occasional mental abnormalities, itchy skin, myalgia, severe abdominal pain (sometimes misdiagnosed as pancreatitis), polyuria at night, and weight loss.

Precautions

It is contraindicated in patients with hypercalcemia, hypervitaminosis D, hyperphosphatemia and renal rickets.

Drug Interactions

1. The magnesium in antacids used together with vitamin D can cause hypermagnesemia, especially in patients with chronic renal failure. 2. Barbiturates, phenytoin, anticonvulsants, primidone, etc. can reduce the effect of vitamin D2. When taking anticonvulsants for a long time, vitamin D should be supplemented to prevent osteomalacia. 3. Calcitonin used together with vitamin D can offset the efficacy of the former on hypercalcemia. 4. The use of large doses of calcium or diuretics together with the usual doses of vitamin D may cause hypercalcemia. 5. Cholestyramine, colestipol, mineral oil, sucralfate, etc. can reduce the absorption of vitamin D in the small intestine. 6. Digitalis used together with vitamin D2

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.125 mg (5000 units)

Manufacturer

Shandong Dyne Marine Organism Pharmaceutical Co., Ltd.

  • Founded in:

    1994-10-27
  • Address:

    No. 18, Fuyuan South Road, Rongcheng City, Shandong Province
  • Tax NO.:

    913700006137729862
  • Registered Funds:

    62 million yuan
  • Website:

  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.