Alendronate Sodium Tablets
Function and Efficacy
Used to treat osteoporosis in postmenopausal women. Prevent hip and spinal fractures (spinal compression fractures). Used to treat male osteoporosis to prevent fractures. This product is a bone metabolism regulator, an aminobisphosphonate, which has a strong affinity for hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition.
Ingredients
Alendronate
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Alendronate sodiumIngredients |
Used to treat osteoporosis in postmenopausal women. Prevent hip and spinal fractures (vertebral compression fractures). Used to treat male osteoporosis to prevent fractures. This product is a bone metabolism regulator, an aminobisphosphonate, with a strong affinity for hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit osteoclast activity and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition. More |
121268-17-5 | 38 |
Appearance
This product is white tablets.
Indication
1. For the treatment of osteoporosis in postmenopausal women. 2. For the prevention of hip and spinal fractures (vertebral compression fractures).
Usage and Dosage
Take orally with 200 ml of warm water on an empty stomach at least 30 minutes before breakfast, 10 mg (1 tablet) at a time, once a day.
Adverse Reactions
Abdominal pain, diarrhea, nausea, constipation, indigestion. If not taken according to the prescribed method, esophageal ulcer may occur. Occasionally, blood calcium is reduced, white blood cell count is temporarily increased, and red blood cells and white blood cells in urine are increased.
Precautions
It is contraindicated for patients with esophageal motility disorders such as esophageal achalasia, esophageal stenosis, severe renal damage, and osteomalacia.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
1. Antacids and cathartics often contain calcium or other metal ions such as magnesium and iron, which may affect the absorption of this drug. 2. Combination with aminoglycosides may induce hypocalcemia.
Storage
Store in airtight container. Valid for 42 months.
Packaging Specification
70mg (calculated as alendronic acid)
Validity Period
24 months
Manufacturer
Hainan Quanxing Pharmaceutical Co., Ltd.
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Founded in:
2001-10-29 -
Address:
A06-2, Bonded Area, Haikou City, Hainan Province -
Tax NO.:
91460000730066028H -
Registered Funds:
54.29 million yuan -
Website:
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Email: