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Naloxone Hydrochloride Injection

Function and Efficacy

Opioid receptor specific antagonist, small dose (0.4-0.8 mg) intramuscular or intravenous injection can quickly reverse the effect of morphine, intravenous injection for 1-3 minutes can eliminate respiratory depression and increase respiratory rate. It has a wake-up effect on animals with acute alcohol poisoning.

Ingredients

The main ingredient of this product is sodium chloranol.

Appearance

Colorless clear liquid.

Indication

This product is the most widely used opioid receptor antagonist in clinical practice. It is mainly used for: 1. Rescue acute poisoning by narcotic analgesics, antagonize the respiratory depression of this type of drug, and awaken the patient. 2. Antagonize the residual effects of narcotic analgesics. Newborns are affected by narcotic analgesics in their mothers and suffer respiratory depression, which can be antagonized by this product. 3. Rescue acute ethanol poisoning: intravenous injection of naloxone 0.4-0.6mg can awaken the patient. 4. For those suspected of being addicted to narcotic analgesics, intravenous injection of 0.2-0.4mg can stimulate withdrawal symptoms and has diagnostic value. 5. Awakening effect, which may activate the physiological awakening system through cholinergic effects to awaken the patient, and is used for general anesthesia awakening and anti-shock and some comatose patients.

Usage and Dosage

Intramuscular or intravenous injection. The usual dose for adults is 0.4-0.8 mg once, and children can reduce the dose accordingly. Repeated doses can be given according to the condition. Severe alcohol poisoning: 0.8-1.2 mg, and repeated doses of 0.4-0.8 mg can be given after one hour.

Adverse Reactions

There are almost no adverse reactions, but when used for combined anesthesia awakening, a few patients may experience mild agitation, which may be caused by antagonizing the analgesic effect of analgesics.

Precautions

Not yet clear.

Special Population Medication

Precautions for children: Using this product on children or newborns can reverse the effects of opioids. Children with opioid poisoning have a strong reaction to this product, so they need to be closely monitored for at least 24 hours until this product is completely metabolized.

Drug Interactions

Not yet clear.

Storage

Keep tightly closed in a cool, dark place.

Packaging Specification

1ml:1mg

Validity Period

24 months

Manufacturer

Beijing Sihuan Pharmaceutical Co., Ltd.

  • Founded in:

    1995-12-26
  • Address:

    Room 101, 1st-5th Floor, Building 5, No. 13 Guangyuan West Street, Tongzhou District, Beijing
  • Tax NO.:

    91110112102444497K
  • Registered Funds:

    250 million yuan
  • Email:

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