Nimesulide Dispersible Tablets

This product is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. Its mechanism of action may be related to the inhibition of prostaglandin synthesis, mediator release of leukocytes and oxidative reactions of polymorphonuclear leukocytes.

The main ingredient of this product is nimesulide, and its chemical name is: N-[4-nitro-2-phenoxyphenyl] methanesulfonamide.

This product is off-white to light yellow irregular tablets.

This product is suitable for rheumatoid arthritis and osteoarthritis, pain and inflammation after surgery and acute trauma, pain caused by inflammation of the ear, nose and pharynx, dysmenorrhea, fever caused by upper respiratory tract infection and other symptoms.

Oral administration: 0.05-0.1g at a time, twice a day, after meals. The maximum single dose should not exceed 100mg, and the course of treatment should not exceed 15 days. It is recommended to use the minimum effective dose and the shortest course of treatment to reduce the occurrence of adverse drug reactions.

The main symptoms are heartburn, nausea, and stomach pain, but the symptoms are mild and short-lived, and rarely require discontinuation of treatment. Allergic rashes may occur in rare cases. Dizziness, drowsiness, gastric ulcers or gastrointestinal bleeding, and Stevens-Johnson syndrome may also occur.

1. Patients who are allergic to this product, acetylsalicylic acid or other non-steroidal drugs are contraindicated. 2. Patients with active gastrointestinal bleeding and active peptic ulcer are contraindicated. 3. Patients with severe liver dysfunction and severe renal dysfunction (creatinine clearance <30 ml/min) are contraindicated.

Precautions for children: Children under 12 years old are prohibited from using this medicine. Precautions for pregnancy and lactation: There are no tests to prove whether nimesulide is toxic to the fetus, so it is not recommended for pregnant women. It has not been confirmed whether nimesulide is excreted through breast milk, so it is not recommended for lactating women. Precautions for the elderly: Due to the decline in renal function in elderly patients, the dosage can be appropriately reduced according to the situation.

Due to the high plasma protein binding rate of this product, it may displace other protein-bound drugs. Furosemide affects the absorption of nimesulide, causing the AUC value of nimesulide to decrease by about 25%; fenofibrate, tolbutamide, and salicylic acid can displace nimesulide from plasma proteins, while furosemide, glibenclamide, and therapeutic doses of warfarin have no effect on the binding rate of nimesulide to proteins.

Seal and store in a dry place. The validity period is tentatively one year.

50mg

Tentatively two years.

Hubei Shubang Pharmaceutical Co., Ltd.

• Founded in:

  2012-04-17

• Address:

  No. 1 Sibao Road, Xiantao City

• Tax NO.:

  914290045942134679

• Registered Funds:

  48 million yuan

• Email:

  Log in to view