Sparfloxacin Capsules

This product is a quinolone antibacterial drug. It is a broad-spectrum antibacterial drug. It has obvious antibacterial effects on Gram-positive bacteria including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, and Enterococcus faecalis; it also has good antibacterial effects on Gram-negative bacteria Escherichia coli, Klebsiella, Salmonella, Shigella, Vibrio parahaemolyticus, Proteus, Enterobacter, Pseudomonas, Acinetobacter, Neisseria (Neisseria gonorrhoeae, etc.). This product also has good antibacterial effects on mycoplasma, chlamydia, Legionella, anaerobic bacteria including Bacteroides fragilis and Mycobacterium. The mechanism of action of this product is to inhibit the action of DNA gyrase in the process of bacterial DNA synthesis and play a bactericidal role.

Sparfloxacin. Chemical name: 5-amino-1-cyclopropyl-7-(cis-3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Molecular weight: C19H22F2N4O3

This product is in the form of capsules.

This product can be used for mild and moderate infections caused by sensitive bacteria, including: 1. Respiratory system infections: such as acute pharyngitis, acute tonsillitis, otitis media, sinusitis, bronchitis, bronchiectasis infection, pneumonia, etc. 2. Intestinal infections: such as bacterial dysentery, typhoid fever, infectious enteritis, salmonella enteritis, etc. 3. Biliary tract infections: such as cholecystitis, cholangitis, etc. 4. Urogenital system infections: such as cystitis, pyelonephritis, prostatitis, gonococcal Neisseria urethritis, non-gonococcal Neisseria urethritis, adnexitis, intrauterine infection, cervicitis, vestibular gland inflammation, etc. and urogenital tract infections caused by Ureaplasma urealyticum and Chlamydia trachomatis. 5. Skin and soft tissue infections: such as impetigo, acne vulgaris, folliculitis, furuncle, furuncle, carbuncle, erysipelas, cellulitis, lymphadenitis, lymphangitis, subcutaneous abscess, hidradenitis, mastitis, trauma and surgical wound infection, etc. 6. Oral infections: such as periodontitis, pericoronitis, palatitis, etc.

For adults, take orally 0.1-0.3g at a time, not more than 0.4g at most, once a day. The course of treatment is generally 5-10 days. The course of treatment can be appropriately increased or decreased according to the type of disease and condition.

1 Digestive system reactions: such as nausea, vomiting, lack of appetite, upper abdominal discomfort, soft stools, diarrhea, abdominal distension, constipation, bloody stools, stomatitis, etc. 2 Allergic reactions: such as rash, fever, local redness, edema, itching, blisters, erythema, photosensitivity reaction, congestion, etc. 3 Central nervous system: headache, dizziness, irritability, insomnia, cramps, tremors, etc. 4 Laboratory tests: GOT, GPT, ALP, LDH, BUN, γ-CTP, serum creatinine and total bilirubin increased, and may also cause eosinophilia and decreased white blood cells, red blood cells, hemoglobin and platelets; there are reports of mild QT prolongation abroad. 5 Others: occasionally tendinitis, pseudomembranous colitis, interstitial pneumonia, shock, allergic syndrome (dyspnea, edema, hoarseness, flushing, pruritus, etc.), eye mucosal syndrome (Stevens-Johnson syndrome), hypoglycemia, numbness, discomfort, fatigue, etc.

It is contraindicated for patients who are allergic to quinolones, pregnant women, lactating women, and patients under 18 years of age.

Precautions for children: Fluoroquinolones can cause permanent damage to the cartilage of the weight-bearing joints of dogs, leading to lameness. They can also cause arthritis in several other underage animals, so they are contraindicated in infants and children under 18 years old. Precautions for pregnancy and lactation: Fluoroquinolones can pass through the blood-placental barrier and can be secreted into breast milk. Their concentration is close to the blood drug concentration, so they are contraindicated for pregnant and lactating women. Precautions for the elderly: Elderly patients have reduced renal function, so the dosage should be reduced as appropriate.

1 Like enoxacin, norfloxacin and ciprofloxacin, there are rare reports of spasms when this product is used in combination with non-steroidal anti-inflammatory drugs (such as fenbutyric acid, propionic acid derivatives, etc.). 2 When this product is used in combination with antacids containing aluminum, magnesium, and iron and sucralfate, the absorption of this product can be reduced, thereby reducing the efficacy. If it is necessary to take it, it should be taken at an interval of 4 hours. 3 When this product is used in combination with theophylline, caffeine, warfarin, and cimetidine, it does not affect the plasma concentration of the latter. 4 The pharmacokinetics of this product are not affected by the combination with digoxin and probenecid. 5 Nutritional supplements containing metal ions and vitamins containing zinc, iron, and calcium can be taken 4 hours after taking this product. 6 This product should not be used in combination with astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines, tricyclic antidepressants, disopyramide, and amiodarone.

Keep in a light-proof and airtight container.

0.1g

24 months

Bright Future Pharmaceutical(Hainan) Co., Ltd.

• Founded in:

  1992-10-12

• Address:

  No. 2, Yaogu 1st Road, Yaogu Industrial Park, Haikou National High-tech Industrial Development Zone

• Tax NO.:

  914600009840920311

• Registered Funds:

  60 million yuan

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