Diphylline Injection
Function and Efficacy
The antiasthmatic effect of this product is similar to that of theophylline. The cardiac stimulant effect is only 1/20~1/10 of that of aminophylline. It has less effect on the heart and nervous system. It is especially suitable for asthma patients with tachycardia. This product has a direct relaxant effect on the smooth muscle of the respiratory tract. Its mechanism of action is relatively complex. In the past, it was believed that it was caused by inhibiting phosphodiesterase and increasing the intracellular cAMP content. Recent experiments have shown that the bronchodilator effect of theophylline is partly due to the release of endogenous adrenaline and noradrenaline. In addition, theophylline is a purine receptor blocker that can counteract the contractile effect of adenine and other substances on the respiratory tract. Theophylline can enhance the contraction force of the diaphragm, especially when the diaphragm contraction is weak, so it helps to improve respiratory function.
Ingredients
The main ingredient of this product is dihydroxypropylphylline, and its chemical name is 1,3-dimethyl-7-(2,3-dihydroxypropyl)-3,7-dihydro-1H-purine-2,6-dione
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| DiprophyllineIngredients |
The antiasthmatic effect is similar to that of theophylline, and the cardiac stimulant effect is only 1/20~1/10 of that of aminophylline. It has less effect on the heart and nervous system and is suitable for asthma patients with tachycardia. It has a direct relaxant effect on the smooth muscle of the respiratory tract, partly by inhibiting phosphodiesterase to increase intracellular cAMP, and releasing endogenous adrenaline and norepinephrine to achieve bronchial dilation. At the same time, theophylline is a purine receptor blocker that can counteract the contractile effect of adenine on the respiratory tract, and can also enhance the contractility of the diaphragm and improve respiratory function. More |
479-18-5 | 11 |
Appearance
This product is a colorless clear liquid.
Indication
It is suitable for bronchial asthma, asthmatic bronchitis, obstructive pulmonary emphysema, etc. to relieve wheezing symptoms. It is also used for asthma caused by cardiogenic pulmonary edema.
Usage and Dosage
Intravenous drip, 0.25-0.75 g (1-3 vials) at a time, diluted with 5% or 10% glucose injection.
Adverse Reactions
Similar to theophylline, excessive doses may cause nausea, vomiting, irritability, insomnia, tachycardia, arrhythmia, and even fever, dehydration, convulsions, and even respiratory and cardiac arrest.
Precautions
It is contraindicated in patients who are allergic to this product, those with active peptic ulcers and uncontrolled convulsive diseases.
Drug Interactions
1. When used in combination with lithium salts, it can increase the renal excretion of lithium and affect the effect of lithium salts. 2. When used in combination with caffeine or other xanthine drugs, it can increase their effects and toxicity.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
2ml:0.25g
Manufacturer
Shiyao YINHU Pharmaceutical Co., Ltd.
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Founded in:
2009-05-25 -
Address:
No. 11, Nanfeng Avenue, Salt Lake High-tech Industrial Development Zone, Yuncheng City, Shanxi Province -
Tax NO.:
91140800689853854G -
Registered Funds:
150 million yuan -
Website:
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Email: