Piroxicam Capsules
Function and Efficacy
It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. This product has a pharmacological effect by inhibiting cyclooxygenase to reduce the synthesis of local prostaglandins in tissues and inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. The analgesic and detumescent effects of this product in the treatment of arthritis are similar to those of indomethacin, aspirin and naproxen. Acute toxicity test results: The oral LD50 of mice is 360mg/kg.
Ingredients
The main ingredients of this product and their chemical names are: The main ingredient is piroxicam, and its chemical name is 2-methyl-4-hydroxy-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| PiroxicamIngredients |
It is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. This product exerts its pharmacological effects by inhibiting cyclooxygenase, reducing the synthesis of prostaglandins in local tissues, and inhibiting the chemotaxis of leukocytes and the release of lysosomal enzymes. More |
36322-90-4 | 33 |
Appearance
This product is in capsule form.
Indication
Used for symptomatic treatment of pain and swelling in various arthritis and soft tissue lesions.
Usage and Dosage
Oral adult dosage: 20 mg once a day, or 10 mg twice a day. Take after meals.
Adverse Reactions
1 Gastrointestinal adverse reactions such as nausea, stomach pain, decreased appetite and indigestion are the most common, of which 3.5% require drug withdrawal. The incidence of gastric ulcer increases significantly when the dosage is greater than 20 mg per day, and some are accompanied by bleeding or even perforation. 2 Neutropenia, eosinophilia, increased blood urea nitrogen, dizziness, vertigo, tinnitus, headache, general weakness, edema, rash or itching, etc., with an incidence of 1% to 3%. 3 Abnormal liver function, thrombocytopenia, hyperhidrosis, skin ecchymosis, peeling, erythema multiforme, toxic epithelial necrosis, bullous erythema multiforme (Stevens-Johnson syndrome), skin allergic reaction to light, blurred vision, redness and swelling of the eyes, hypertension, hematuria, hypotension
Precautions
It is contraindicated for patients who are allergic to this product, have peptic ulcers, or chronic gastric diseases.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: 1. Pregnant women who take the drug in the last three months of pregnancy may inhibit labor and cause dystocia, and may also experience gastrointestinal toxicity. In addition, long-term use of the drug in the late pregnancy may cause early closure or stenosis of the fetal ductus arteriosus, resulting in persistent pulmonary hypertension and heart failure in the newborn. Pregnant women are prohibited from using it. 2. This product can cause a decrease in milk secretion, which is related to the dosage. It is not suitable for lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
1. When drinking alcohol or taking it with other anti-inflammatory drugs, gastrointestinal adverse reactions increase. 2. When used with anticoagulants such as dicoumarol, the latter's effect is enhanced and the bleeding tendency is significant, so the dosage should be adjusted. 3. When used with aspirin, the blood concentration of this product can drop to 80% of the normal concentration, and the risk of gastrointestinal ulcer formation and bleeding tendency increases.
Storage
Keep away from light and store in sealed container.
Packaging Specification
10mg
Validity Period
24 months
Manufacturer
Hainan Boda Pharmaceutical Factory
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Founded in:
1996-10-24 -
Address:
No. A-8, Haikou National High-tech Industrial Development Zone -
Tax NO.:
914600009840901593 -
Registered Funds:
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Website:
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Email: