On ECHEMI
Home > Drugs > Phenolamine tablets

Phenolamine tablets

Function and Efficacy

The aminopyrine in this product can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the sensory neurons in the thermoregulatory center, and have an antipyretic effect; at the same time, it also has an analgesic effect by inhibiting the synthesis of prostaglandins, etc. Aminopyrine can also inhibit the synthesis and release of prostaglandins in local tissues of inflammation, stabilize lysosomal enzymes, and affect the phagocytic function of phagocytes to play an anti-inflammatory role. Acetaminophen is a peripheral analgesic. The mechanism of action is to inhibit the synthesis and release of prostaglandins (PGE1) in the thermoregulatory center of the hypothalamus, thereby causing peripheral vasodilation and sweating to achieve an antipyretic effect. At the same time, it can inhibit the effects of PGE1, bradykinin and histamine, etc., increase the pain threshold and produce analgesic effects. Caffeine is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, enhancing the effect of the first two drugs in relieving headaches. Chlorpheniramine maleate has a strong histamine H1 receptor blocking effect, which can alleviate other respiratory symptoms caused by allergies and also has a mild inhibitory effect on the central nervous system.

Ingredients

This product is a compound preparation, its components are: acetaminophen 0.15g, aminopyrine 0.1g, caffeine 30mg, chlorpheniramine maleate 2mg.

Name Description Content CAS NO. Manufacturer
AcetaminophenIngredients

It is a peripheral analgesic that inhibits the synthesis and release of prostaglandins (PGE1) in the hypothalamic temperature regulation center, causing peripheral vasodilation and sweating to achieve an antipyretic effect. It can also inhibit the effects of PGE1, bradykinin and histamine, increase the pain threshold and produce analgesic effect.

More
103-90-2 68
Chlorphenamine maleateIngredients

It has a strong histamine H1 receptor blocking effect, can alleviate other respiratory symptoms caused by allergies, and also has a mild inhibitory effect on the central nervous system.

More
113-92-8 28

Appearance

This product is white tablets.

Indication

Used for colds, fever, headaches, neuralgia and rheumatism, etc.

Usage and Dosage

Oral administration. 1 tablet at a time, 3 times a day or as directed by your doctor.

Adverse Reactions

The aminopyrine contained in this compound has obvious adverse reactions. Taking aminopyrine may cause vomiting, rash, fever, heavy sweating and stomatitis, etc. In a few cases, it may cause neutropenia, aplastic anemia, exudative erythema, exfoliative dermatitis, glans erosion, etc.

Precautions

1. Patients allergic to aminopyrine, caffeine, and chlorpheniramine maleate are prohibited from using this product. 2. Patients with gastric ulcer are prohibited from using this product. 3. Neonates or premature infants are prohibited from using this product.

Special Population Medication

Precautions for children: It is forbidden to use in newborns or premature infants. Precautions for pregnancy and lactation: A small amount of chlorpheniramine can be excreted in breast milk. Since this product has an anti-M cholinergic receptor effect, lactation may be inhibited, so it should be used with caution in lactating women. Precautions for the elderly: The elderly are more sensitive to the commonly used doses and should pay attention to appropriate reductions.

Drug Interactions

1 Isoniazid and meprobamate can enhance the efficacy of caffeine, increasing the concentration of the latter in brain tissue by 55%, while the concentration in liver and kidney decreases. 2 Oral contraceptives may slow down the clearance rate of caffeine. 3 Drinking alcohol or taking central nervous system depressants at the same time can enhance the efficacy of antihistamines. 4 This product can enhance the effects of adamantane, anticholinergics, haloperidol, phenoxylates and sympathomimetic drugs. 5 When quinidine is used together with this product, its atropine-like effect is intensified. 6 Taking this product together with tricyclic antidepressants can enhance the efficacy of the latter.

Storage

Keep away from light and store in sealed container.

Packaging Specification

Compound

Validity Period

24 months

Manufacturer

Sichuan Shuzhong Pharmaceutical Co., Ltd.

  • Founded in:

    1997-09-15
  • Address:

    No. 113, Group 10, Jing'an Village, Mazu Town, Shifang City, Deyang City, Sichuan Province
  • Tax NO.:

    915106827446699545
  • Registered Funds:

    50 million yuan
  • Email:

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.