Fluorescein Sodium Injection

This product is a diagnostic drug and a dye. It cannot dye normal corneal epithelium, but can dye damaged corneal epithelium green, thus showing corneal damage, ulcers and other lesions. When flowing through small blood vessels, it can pass through thinner blood vessel walls and mucous membranes under ultraviolet or blue light excitation to exhibit green fluorescence, thereby showing the course and morphology of small blood vessels, etc., which can be used for fundus angiography and circulation time measurement. This product can hardly pass through the blood-brain barrier, but its content in cerebrospinal fluid increases in tuberculous meningitis. Determination of the content of this product in cerebrospinal fluid after intramuscular injection is helpful for the diagnosis and differential diagnosis of tuberculous meningitis.

Fluorescein sodium

This product is orange-red powder; odorless, almost tasteless; hygroscopic

It is used for diagnosis of corneal injury, ulcer and foreign body, fundus angiography and circulation time measurement. It is also used for intraoperative display of gallbladder and bile duct, and auxiliary diagnosis of tuberculous meningitis.

1. Determination of circulation time: Injection into forearm vein, the usual dosage for adults is 5ml (10%). The usual dosage for children is 0.05ml/kg (10%) according to body weight, and the whole dosage is quickly pushed in within 1 second. 2. Intravenous injection for fundus angiography: the usual dosage for adults is 5ml (10%), or calculated according to body weight of 15-30mg/kg, and the whole dosage is pushed in about 4 seconds. 8 seconds after injection, continuous photography is performed with a fluorescent fundus camera under the stimulation of blue light waves, starting with 1 picture per second for 10 seconds, and then taking pictures at appropriate intervals within 30 minutes. Direct observation with an ophthalmoscope is also possible. It is shown in the figure that 5 ml (10%4) is injected intravenously 4 hours before gallbladder and bile duct surgery. Cerebrospinal fluid permeability test (diagnosis of tuberculous meningitis) is injected intramuscularly. The recommended dosage for adults is 5-10 ml (10%). The recommended dosage for children is 0.3 ml/kg (10%) based on body weight. Cerebrospinal fluid is extracted by lumbar puncture 2 hours after injection and compared with a standard series of colorimetric tubes with concentrations of 0.00001%, 0.00002%, 0.00003%, 0.00005%, 0.00006%, 0.0001%, 0.0002% and 0.0005%.

Allergic reactions to this product include: urticaria, dyspnea, asthma attack, respiratory arrest, hypotension, shock, cardiac arrest, myocardial infarction, pulmonary edema and cerebral infarction. Common reactions include nausea, vomiting and dizziness, which usually occur within 30 seconds after injection. The incidence and severity of the reaction are related to the concentration and injection volume of the injection. A single intravenous injection of 5ml (5%) often causes nausea and vomiting. The total incidence of reactions during angiography of this product is about 0.6%, and the severe reaction is about 0.4%. There may be local pain after intramuscular injection. After intravenous injection, the skin and urine are temporarily stained, and objects appear yellow or pink.

1. Those who are allergic to this product are prohibited from using it; 2. Those with a history of asthma and other allergic diseases are prohibited from using it; 3. Those with severe liver and kidney damage are prohibited from using it. 4. When measuring blood circulation, patients with congenital ischemic heart disease and pregnant women are prohibited from using it.

This product should not be mixed with acids, acid salts and heavy metal salts.

Keep tightly closed.

3ml:0.6g

Guangzhou Baiyunshan Mingxing Pharmaceutical Co., Ltd.

• Founded in:

  1962-12-27

• Address:

  No. 48, North Industrial Avenue, Haizhu District, Guangzhou

• Tax NO.:

  9144010119046020XE

• Registered Funds:

  46.091897 yuan

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