Folic acid tablets

Folic acid is a water-soluble B vitamin composed of pteridine, p-aminobenzoic acid and glutamic acid residues. It is an essential substance for the growth and reproduction of body cells. It exists in the liver, kidney, yeast and green leafy vegetables such as beans, spinach, tomatoes, carrots, etc., and can now be synthesized artificially. Folic acid is converted into tetrahydrofolate (THFA) by the action of dihydrofolate reductase and vitamin B12. The latter combines with a variety of one-carbon units (including CH3, CH2, CHO, etc.) to form tetrahydrofolate coenzymes, transfer one-carbon units, and participate in many important reactions in the body and the synthesis of nucleic acids and amino acids. THFA forms N5,10-methyltetrahydrofolate under the action of serine transhydroxylase, which can promote the formation of thymine nucleotides (dTMP) from uracil nucleotides (dUMP). The latter can participate in the DNA synthesis of cells and promote cell division and maturation. During the DNA synthesis process, deoxyuridylic acid is converted into deoxythymidylic acid, and the methyl group required is provided by methylenetetrahydrofolate. When folic acid is deficient, DNA synthesis slows down, but RNA synthesis is not affected. As a result, blood cells with larger cell size and more immature nuclei are produced in the bone marrow, especially red blood cells. Timely supplementation can have a therapeutic effect.

Each tablet of this product contains 0.4 mg of folic acid. Excipients are: starch, lactose, magnesium stearate.

This product is yellow or orange-yellow tablets.

⑴ Folic acid deficiency caused by various reasons and megaloblastic anemia caused by folic acid deficiency; ⑵ Preventive medication for pregnant and lactating women; ⑶ Folic acid deficiency caused by chronic hemolytic anemia;

1. Prevention of congenital neural tube defects in the fetus: Oral administration, women of childbearing age, 0.4 mg once a day from the time of pregnancy planning to the end of the third month of pregnancy. 2. Preventive medication for pregnant and lactating women: 0.4 mg once a day.

There are few adverse reactions, and allergic reactions are rare. Long-term use may cause gastrointestinal symptoms such as loss of appetite, nausea, and bloating. When taking large amounts of folic acid, urine may turn yellow.

Megaloblastic anemia caused by vitamin B12 deficiency cannot be treated with folic acid alone.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: This product can be used. Precautions for the elderly: Not yet clear.

⑴ Large doses of folic acid can antagonize the anti-epileptic effects of phenobarbital, phenytoin sodium and primidone, significantly reduce the critical value of epileptic seizures, and increase the number of seizures in sensitive patients; ⑵ Oral administration of large doses of folic acid can affect the absorption of the trace element zinc.

Keep away from light and store in sealed container.

0.4 mg

36 months.

ORxes Biopharmaceuticals (Shenyang) Co., Ltd.

• Founded in:

  2004-08-09

• Address:

  No. 176, Shenbei Road, Huishan Economic Development Zone, Shenbei New District, Shenyang

• Tax NO.:

  91210100764362386F

• Registered Funds:

  115 million yuan

• Email:

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