Recombinant human interferon α2b injection
Function and Efficacy
Pharmacological effects: The results of preclinical cell culture systems and animal xenogeneic tumor transplantation experiments showed that recombinant human interferon α2b has anti-tumor proliferation effects and has obvious immunomodulatory effects in vitro. In vitro studies have also shown that recombinant human interferon α2b can inhibit viral replication. Interferon produces the above effects by binding to specific membrane receptors on the cell surface. Many studies have suggested that once interferon binds to cell receptors, it can initiate a series of complex intracellular processes, including the induction of certain enzymes. It is believed that this process, at least to some extent, leads to various cellular responses of interferon, including inhibition of viral replication in virus-infected cells, inhibition of cell proliferation, and a series of immunomodulatory effects, such as enhancing the action of macrophages and lymphocytes on target cells.
Ingredients
Recombinant human interferon alpha 2b, polysorbate 80, and benzyl alcohol.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Tween 80Excipients |
Pharmacological effects: The results of preclinical cell culture systems and animal xenogeneic tumor transplantation experiments showed that recombinant human interferon α2b has anti-tumor proliferation effects and has obvious immunomodulatory effects in vitro. In vitro studies have also shown that recombinant human interferon α2b can inhibit viral replication. Interferon produces the above effects by binding to specific membrane receptors on the cell surface. Many studies have suggested that once interferon binds to cell receptors, it can initiate a series of complex intracellular processes, including the induction of certain enzymes. It is believed that this process, at least to some extent, leads to various cellular responses of interferon, including inhibition of viral replication in virus-infected cells, inhibition of cell proliferation, and a series of immunomodulatory effects, such as enhancing the action of macrophages and lymphocytes on target cells. More |
9005-65-6 | 17 | |
| Benzyl alcoholExcipients |
Pharmacological effects: The results of preclinical cell culture systems and animal xenogeneic tumor transplantation experiments showed that recombinant human interferon α2b has anti-tumor proliferation effects and has obvious immunomodulatory effects in vitro. In vitro studies have also shown that recombinant human interferon α2b can inhibit viral replication. Interferon produces the above effects by binding to specific membrane receptors on the cell surface. Many studies have suggested that once interferon binds to cell receptors, it can initiate a series of complex intracellular processes, including the induction of certain enzymes. It is believed that this process, at least to some extent, leads to various cellular responses of interferon, including inhibition of viral replication in virus-infected cells, inhibition of cell proliferation, and a series of immunomodulatory effects, such as enhancing the action of macrophages and lymphocytes on target cells. More |
100-51-6 | 20 |
Appearance
Colorless clear liquid.
Indication
It can be used to treat chronic hepatitis B, chronic hepatitis C, genital warts, hairy cell leukemia, and chronic myeloid leukemia.
Usage and Dosage
Intramuscular or subcutaneous injection: 1 Chronic hepatitis B: The recommended dose is 3 to 5 million international units (IU) each time, injected once a day or every other day. A course of treatment is 3 to 6 months, and the doctor can adjust the dose according to the patient's specific situation. 2 Chronic hepatitis C: The recommended dose is 3 to 5 million international units (IU) each time, injected once a day or every other day. A course of treatment is 3 to 6 months, and the doctor can adjust the dose according to the patient's specific situation. 3 Genital warts: The recommended dose is 1 to 3 million international units (IU) each time, injected three times a week every other day. A course of treatment is 1 to 2 months. 4 Hairy cell leukemia: Recommended
Adverse Reactions
1. The most common adverse reactions to this product include fever, chills, fatigue, headache, muscle aches, anorexia and other flu-like symptoms. Taking antipyretic and analgesic drugs (paracetamol, etc.) can alleviate or eliminate these symptoms. These symptoms can also be alleviated with continued medication or dosage adjustment. 2. Common abnormal hematological indicators include leukopenia, thrombocytopenia and increased transaminase. 3. Once an allergic reaction occurs, the medication should be stopped immediately and appropriate treatment should be given. 4. According to literature reports, other adverse reactions of alpha interferon include: diarrhea, nausea, hypertension, hypotension, vomiting, joint pain, impaired perception, mental confusion, dizziness, movement disorders, paresthesia, anxiety, depression,
Precautions
1. Patients with a history of allergy to interferon α2b or other ingredients of this preparation are contraindicated. 2. Patients with severe heart, liver, kidney and bone marrow dysfunction and patients with central nervous system dysfunction should not use this product.
Special Population Medication
Precautions for children: Due to limited experience in using this product for patients under 18 years of age, the pros and cons should be carefully weighed when using this product. Precautions for pregnancy and lactation: 1. There is no data to show whether the use of this product in pregnant women will affect the fetus. This product can only be used when the benefits of the drug to the mother outweigh the potential risks to the fetus. 2. There is no data to show whether interferon is secreted through breast milk after using this product. When breastfeeding women need to use the drug, they should consider the importance of this product to the mother and decide whether to stop breastfeeding or stop taking the drug. Precautions for the elderly: This product has not been tested and there is no reliable reference.
Drug Interactions
Not yet clear
Storage
Store in a dark place at 2-8℃, valid for 24 months
Packaging Specification
3 million IU/0.3ml
Validity Period
24 months
Manufacturer
ChangChun Heber Biological Technology Co., Ltd.
-
Founded in:
2003-12-08 -
Address:
No. 11111, Gangcheng Street, Airport Economic Development Zone, Changchun New Area, Jilin Province -
Tax NO.:
91220101748448227C -
Registered Funds:
383.634129 yuan -
Website:
-
Email: