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Human fibrinogen

Function and Efficacy

During the coagulation process, fibrinogen is hydrolyzed by thrombin into fibrin. Under the action of fibrin-stabilizing factor (FXIII), solid fibrin is formed, which plays an effective hemostatic role.

Ingredients

Main components: human fibrinogen.

Appearance

This product is a loose body of off-white or light yellow. After reconstitution, it should be a clear liquid with a slight opalescence.

Indication

1. Congenital hypofibrinogenemia or deficiency. 2. Acquired hypofibrinogenemia: severe liver damage; liver cirrhosis; disseminated intravascular coagulation; postpartum hemorrhage and coagulation disorders caused by fibrinogen deficiency due to major surgery, trauma or internal bleeding.

Usage and Dosage

Usage: Preheat the product and sterile water for injection to 30-37℃ before use, then inject the preheated sterile water for injection according to the amount indicated on the bottle label, place in a 30-37℃ water bath, and gently shake to dissolve the product completely (avoid violent shaking to avoid protein denaturation). Use an infusion set with a filter device for intravenous drip. The drip rate is generally about 60 drops per minute. Dosage: It should be determined according to the condition and clinical test results. Generally, 1-2g is given for the first time. If necessary, continue to give the drug according to the doctor's advice.

Adverse Reactions

Generally there are no adverse reactions. Only a few patients with allergic constitutions will experience allergic reactions. Emergency treatment measures should be taken for those with severe reactions.

Precautions

There are no known contraindications when the indications are strictly controlled.

Special Population Medication

Precautions for children: No research data available. Precautions for pregnancy and lactation: Pregnant and lactating women should use the drug with caution. It should only be used when it is necessary for the patient after weighing the pros and cons, and should be used under the guidance of a physician and close observation. Precautions for the elderly: No research data available.

Drug Interactions

Do not use with other medicines.

Storage

It should be stored in a dry place away from light at a temperature below 10°C. Use within the expiration date indicated on the bottle label.

Packaging Specification

0.5g/bottle

Validity Period

24 months

Manufacturer

Harbin Pesfico Biopharmaceutical Co., Ltd.

  • Founded in:

    1992-05-27
  • Address:

    No. 77 Siping Road, Limin Economic and Technological Development Zone, Harbin
  • Tax NO.:

    91230100607160107E
  • Registered Funds:

    80.871606 million yuan
  • Website:

  • Email:

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