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Ambroxol Hydrochloride Dispersible Tablets

Function and Efficacy

⑴ Stimulate the bronchial mucous glands, increase the secretion of neutral mucopolysaccharides, reduce the synthesis of acidic mucopolysaccharides and promote their metabolism, so that the physical and chemical properties of respiratory mucus tend to normal, which is conducive to discharge. ⑵ Stimulate alveolar epithelial cells and Clara cells, promote the synthesis and secretion of alveolar surfactant, activate the synthesis of surfactant by pneumocytes, cover the entire respiratory epithelial cells, and directly protect lung function. Increase the content of phosphatidylcholine in alveolar macrophages, affect lung phospholipid metabolism, while cysteine mucolytics have no such effect. This product also promotes the synthesis and secretion of gastric surfactant. ⑶ Activate the ciliary function of the respiratory mucosa, reduce the adhesion between sputum and cilia, and increase the frequency of ciliary movement by 10.8%, which is conducive to the discharge of respiratory secretions. This product also has the effect of increasing the concentration of antibiotics in lung tissue and its secretions. ⑷ Anti-inflammatory and antioxidant properties In vitro tests have shown that ambroxol has the effect of reducing the secretion of cytokines IL-1, TNF-a, and IF-Y in activated alveolar cells in bronchopulmonary lavage fluid and peripheral blood mononuclear cells; inhibiting the production of IL-1 and TNF in human mononuclear cells in vitro; and has a significant inhibitory effect on the release of inflammatory mediators such as arachidonic acid oxidation products produced by ozone-induced airway hyperresponsiveness. Ambroxol can protect against lung damage caused by peroxides, including asthma, and improve the antioxidant activity of lung tissue. It is an effective anti-lipid peroxidation agent.

Ingredients

trans-4-[(2-amino-3,5-dibromophenyl)methyl-amino]-cyclohexanol hydrochloride

Appearance

This product is white or off-white tablets.

Indication

Suitable for people with thick sputum that is difficult to cough up.

Usage and Dosage

Oral administration: 1. Adults: 30 mg once, 3 times a day. Long-term users can reduce the dose to 2 times a day. 2. Children: Children over 12 years old take the same dose as adults. The recommended dose for children under 12 years old is 1.2 to 1.6 mg per kilogram of body weight per day.

Adverse Reactions

Allergic reactions rarely occur, mainly rash.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Taking this product with antibiotics (amoxicillin, cefuroxime, erythromycin, doxycycline) at the same time may increase the concentration of antibiotics in lung tissue. 2. If you are taking other medicines, please consult a doctor or pharmacist before using this product.

Storage

Keep sealed.

Packaging Specification

30 mg

Validity Period

36 months

Manufacturer

Tongliao Huabang Pharmaceutical Co., Ltd.

  • Founded in:

    2005-04-15
  • Address:

    Tiedong, Ganqika Town, Kezuohou Banner, Tongliao City, Inner Mongolia Autonomous Region
  • Tax NO.:

    91150522772224493R
  • Registered Funds:

    50 million yuan
  • Email:

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