Pyridostigmine Bromide Tablets
Function and Efficacy
This drug is a reversible anticholinesterase drug that can inhibit the activity of cholinesterase, reduce the destruction of acetylcholine released from cholinergic nerve endings, accumulate acetylcholine in the synaptic cleft, and produce muscarinic (M) and nicotinic (N) cholinergic receptor excitation. In addition, it has a direct excitatory effect on nicotinic cholinergic receptors (N2 receptors) on the motor end plate, and can promote the release of acetylcholine from motor nerve endings, thereby increasing the muscle tension of gastrointestinal tract, bronchial smooth muscle and skeletal muscle throughout the body. Although the effect is weaker than that of neostigmine bromide, it lasts longer.
Ingredients
The main ingredient of this product is pyridostigmine bromide.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| MestinonIngredients |
Reversible anticholinesterase drugs can inhibit the activity of cholinesterase, reduce the destruction of acetylcholine released from cholinergic nerve endings, accumulate acetylcholine in the synaptic cleft, and cause excitatory effects on muscarinic (M) and nicotinic (N) cholinergic receptors. In addition, it has a direct excitatory effect on nicotinic cholinergic receptors (N2 receptors) on motor end plates, and can promote the release of acetylcholine from motor nerve endings, thereby increasing the muscle tension of gastrointestinal tract, bronchial smooth muscle and skeletal muscle throughout the body. Although the effect is weaker than that of neostigmine bromide, it lasts longer. More |
101-26-8 | 25 |
Indication
Used for myasthenia gravis, functional intestinal flatulence and urinary retention after surgery, etc.
Usage and Dosage
Oral administration: Generally, adults take 60-120 mg (1-2 tablets) once every 3-4 hours.
Adverse Reactions
1. Common symptoms include diarrhea, nausea, vomiting, stomach cramps, increased sweating and salivation, etc. Less common symptoms include frequent urination, miosis, etc. 2. Myasthenia gravis patients who receive high-dose treatment often develop mental abnormalities.
Precautions
It is contraindicated for patients with angina pectoris, bronchial asthma, mechanical intestinal obstruction and urinary tract obstruction.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
60mg
Validity Period
24 months
Manufacturer
Shanghai Sine Pharmaceutical Laboratories Co., Ltd.
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Founded in:
1993-10-23 -
Address:
No. 905, Xinjinqiao Road, China (Shanghai) Pilot Free Trade Zone -
Tax NO.:
91310000133742534B -
Registered Funds:
1,191,611,312 yuan -
Website:
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Email: