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Pyridostigmine Bromide Tablets

Function and Efficacy

This drug is a reversible anticholinesterase drug that can inhibit the activity of cholinesterase, reduce the destruction of acetylcholine released from cholinergic nerve endings, accumulate acetylcholine in the synaptic cleft, and produce muscarinic (M) and nicotinic (N) cholinergic receptor excitation. In addition, it has a direct excitatory effect on nicotinic cholinergic receptors (N2 receptors) on the motor end plate, and can promote the release of acetylcholine from motor nerve endings, thereby increasing the muscle tension of gastrointestinal tract, bronchial smooth muscle and skeletal muscle throughout the body. Although the effect is weaker than that of neostigmine bromide, it lasts longer.

Ingredients

The main ingredient of this product is pyridostigmine bromide.

Name Description Content CAS NO. Manufacturer
MestinonIngredients

Reversible anticholinesterase drugs can inhibit the activity of cholinesterase, reduce the destruction of acetylcholine released from cholinergic nerve endings, accumulate acetylcholine in the synaptic cleft, and cause excitatory effects on muscarinic (M) and nicotinic (N) cholinergic receptors. In addition, it has a direct excitatory effect on nicotinic cholinergic receptors (N2 receptors) on motor end plates, and can promote the release of acetylcholine from motor nerve endings, thereby increasing the muscle tension of gastrointestinal tract, bronchial smooth muscle and skeletal muscle throughout the body. Although the effect is weaker than that of neostigmine bromide, it lasts longer.

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Indication

Used for myasthenia gravis, functional intestinal flatulence and urinary retention after surgery, etc.

Usage and Dosage

Oral administration: Generally, adults take 60-120 mg (1-2 tablets) once every 3-4 hours.

Adverse Reactions

1. Common symptoms include diarrhea, nausea, vomiting, stomach cramps, increased sweating and salivation, etc. Less common symptoms include frequent urination, miosis, etc. 2. Myasthenia gravis patients who receive high-dose treatment often develop mental abnormalities.

Precautions

It is contraindicated for patients with angina pectoris, bronchial asthma, mechanical intestinal obstruction and urinary tract obstruction.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Not yet clear.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

60mg

Validity Period

24 months

Manufacturer

Shanghai Sine Pharmaceutical Laboratories Co., Ltd.

  • Founded in:

    1993-10-23
  • Address:

    No. 905, Xinjinqiao Road, China (Shanghai) Pilot Free Trade Zone
  • Tax NO.:

    91310000133742534B
  • Registered Funds:

    1,191,611,312 yuan
  • Website:

  • Email:

Other Drugs of Shanghai Sine Pharmaceutical Laboratories Co., Ltd.

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