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Polygeline injection

Function and Efficacy

This product is a gelatin polypeptide solution with an average molecular weight (Mw) of 27500-39500. Its osmotic pressure is equal to that of plasma, which can maintain the balance between intravascular fluid and interstitial fluid, does not cause tissue dehydration and pulmonary edema, and has the effect of maintaining blood volume and raising blood pressure. Infusion of this product can lead to blood dilution, reduce blood viscosity, and thus improve microcirculation. This product has no significant effect on blood clotting time and platelet function, and only has a blood dilution effect.

Ingredients

This product is a sterilized aqueous solution made from the hydrolysis of healthy bovine or pig bone gelatin.

Name Description Content CAS NO. Manufacturer
GelatinIngredients

The average molecular weight (Mw) should be 27500-39500. Its osmotic pressure is equal to that of plasma, which can maintain the balance between intravascular fluid and interstitial fluid, does not cause tissue dehydration and pulmonary edema, and has the effect of maintaining blood volume and raising blood pressure. Infusion of this product can lead to blood dilution, reduce blood viscosity, and thus improve microcirculation. This product has no significant effect on blood clotting time and platelet function, and only has a blood dilution effect.

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9000-70-8 47

Indication

Used for hemorrhagic shock caused by trauma: fluid loss shock caused by severe burns, sepsis, pancreatitis, etc. This product can be used to prevent hypotension that may occur before major surgery and for volume supplementation during extracorporeal circulation and hemodialysis.

Usage and Dosage

Intravenous drip. 500-1000ml at a time, drip rate is 500ml/60 minutes. The dosage and infusion rate are determined according to the condition, and the maximum daily dosage can reach 2500ml. The dosage for children is based on body weight, 10-20ml/kg.

Adverse Reactions

During or after infusion, transient skin reactions (urticaria), nausea and vomiting, hypotension, tachycardia, bradycardia, dyspnea, fever or chills, shock and other serious reactions may occur occasionally, but they are extremely rare. If the above situations occur, the infusion should be stopped immediately and symptomatic treatment should be given.

Precautions

1. Severe liver and kidney damage, renal or postrenal anuria. 2. Contraindicated in patients with congestive heart failure, pulmonary edema, cardiogenic shock. 3. Contraindicated in patients with hypertension, esophageal varices, and bleeding diseases. 4. Contraindicated in patients with known allergies to this preparation or with high risk factors for histamine release.

Drug Interactions

1 Patients using cardiac glycosides should consider the synergistic effect of calcium with them. 2 Incompatible liquid medicines: ampicillin, bacillus, methylprednisolone, imipramine, acyclovir. 3 This product cannot be mixed with blood containing citrate, but blood containing citrate can be infused before or after this product, or infused simultaneously through different channels.

Storage

Sealed, stored at 2-25℃. Valid for 3 years

Packaging Specification

250ml:1.6g (based on nitrogen content)

Manufacturer

Anhui Fengyuan Pharmaceutical Co., Ltd.

  • Founded in:

    1997-08-30
  • Address:

    No. 188 Tongjiang Avenue, Wuwei City, Wuhu City, Anhui Province
  • Tax NO.:

    91340200153701860P
  • Registered Funds:

    464.773722 million yuan
  • Website:

  • Email:

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