Granisetron Hydrochloride and Sodium Chloride Injection
Function and Efficacy
1. This product is a highly selective 5HT3 receptor antagonist; 2. It has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery; 3. Mechanism of action: factors such as radiotherapy, chemotherapy and surgery can cause enterochromaffin cells to release 5HTTrarr; 5HT can activate the 5HT3 receptors of the central nervous system or vagus nerve and cause vomiting reflexrarr; Granisetron hydrochloride antagonizes the 5HT3 receptors of the central chemoreceptor area and peripheral vagus nerve endingsrarr; inhibits the occurrence of nausea and vomiting; 4. This product has high selectivity and has no side effects such as extrapyramidal reactions and excessive sedation.
Ingredients
Main ingredients: Granisetron hydrochloride
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Granisetron HydrochlorideIngredients |
This product is a highly selective 5HT3 receptor antagonist, which has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. It inhibits the occurrence of nausea and vomiting by antagonizing the 5HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings. It has high selectivity and no side effects such as extrapyramidal reactions and excessive sedation. More |
107007-99-8 | 35 |
Indication
Used for nausea and vomiting caused by radiotherapy and cytotoxic chemotherapy.
Usage and Dosage
For intravenous drip, the adult dose is usually 3 mg, given 30 minutes before treatment. Most patients only need to take the drug once, and the preventive effect on nausea and vomiting can last for more than 24 hours. If necessary, the dose can be increased by 1-2 times, but the maximum daily dose should not exceed 9 mg.
Adverse Reactions
Common side effects include headache, fatigue, fever, constipation, and occasional transient asymptomatic increase in liver transaminases. The reaction is mild and can be recovered without special treatment.
Precautions
1. It is contraindicated for patients with gastrointestinal obstruction. 2. It is contraindicated for patients who are allergic to this product.
Storage
Keep in a light-proof and airtight container.
Packaging Specification
50ml: Granisetron 3mg and sodium chloride 0.45g
Manufacturer
Liaoning Hishen Liansheng Pharmaceutical Co., Ltd.
-
Founded in:
2001-02-27 -
Address:
No. 3, Jinquan Road, Langtou Town, Dandong City -
Tax NO.:
912106007268406746 -
Registered Funds:
30 million yuan -
Website:
-
Email: