Tandospirone Citrate Capsules

Tandospirone is an antianxiety drug that selectively acts on the 5-HT1A receptor in the brain. Animal experiments have shown that tandospirone has comparable antianxiety effects to diazepam. Animal model experiments on psychosomatic diseases have shown that tandospirone can inhibit the pressor response caused by hypothalamic stimulation and the increase in plasma renin activity caused by electric shock stress, and inhibit the occurrence of gastric ulcers caused by psychological stress and the loss of appetite caused by forced immersion stress.

Tandospirone citrate, chemical name: (3aα, 4β, 7β, 7aα)-hexahydro-2-[4(4-(2-pyrimidinyl)-1-piperazinyl)butyl]-4,7-methylene-1hydro-isoindole-1,3(2-hydro)-dione dihydrocitrate

This product is a capsule, and the contents are white powder.

1 Anxiety state caused by various neuroses, such as generalized anxiety disorder. 2 Anxiety state associated with physical complications such as primary hypertension and peptic ulcer.

Generally, adults take 10 mg orally 3 times a day. The dosage may be increased or decreased according to the patient's age, symptoms, etc. The maximum daily dosage should not exceed 60 mg or follow the doctor's advice.

According to foreign literature reports, 150 cases (10.3%) out of a total of 1,451 cases investigated had adverse reactions and abnormal laboratory test values. The main adverse reactions included drowsiness in 43 cases (3.0%), staggering gait in 16 cases (1.1%), nausea in 13 cases (0.9%), fatigue in 11 cases (0.8%), bad mood in 11 cases (0.8%), and decreased appetite in 10 cases (0.7%). The main abnormal laboratory test values included elevated AST (GOT) and ALT (GPT). 1 Severe adverse reactions include abnormal liver function and jaundice (because abnormal liver function and jaundice with elevated AST (GOT), ALT (GPT), AI-P, and γ-GTP may occur,

It is contraindicated for those who are allergic to any ingredient in this product.

Precautions for children: There is no safety data for premature infants, newborns, infants, young children and children. Precautions for pregnancy and lactation: 1. It can only be used for pregnant women or women who may become pregnant after judging that the benefits of treatment outweigh the risks. 2. It is best not to use it for breastfeeding women. If you have to take the medicine, you should avoid breastfeeding. Precautions for the elderly: According to foreign literature reports, in pharmacokinetic tests of elderly patients given 90 mg/day (3 times the commonly used clinical dose), the blood concentration of the elderly is higher than that of young people. Therefore, when used in the elderly, start with a small dose (e.g., 5 mg each time).

Butyrophenone drugs: Haloperidol, spiperonol, etc. may enhance extrapyramidal symptoms. Due to the weak anti-dopamine effect of this drug, it may enhance the pharmacological effects of butyryl drugs. Calcium antagonists: Nicardipine, amlodipine, nifedipine, etc. may enhance the antihypertensive effect. Due to the central antihypertensive effect mediated by 5-hydroxytryptamine receptors, it may enhance the antihypertensive effect.

Keep in a sealed container and shading. The validity period is tentatively 12 months.

10mg

Tentatively 18 months.

Sichuan Credit Pharmaceutical Co., Ltd.

• Founded in:

  2000-04-20

• Address:

  Pharmaceutical Industrial Park, Luzhou National High-tech Zone, Sichuan Province

• Tax NO.:

  915105217144041624

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  27.214286 million yuan

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