Omeprazole enteric-coated tablets

Proton pump inhibitor. This product is a fat-soluble weakly alkaline drug that is easily concentrated in an acidic environment. Therefore, after oral administration, it can be specifically distributed in the secretory tubules of the gastric mucosal parietal cells, and converted into the active form of sulfenamide in this high-acid environment. Then, it irreversibly combines with the sulfhydryl group of the H, K-ATPase (also known as the proton pump) in the secretory membrane of the parietal cells through a disulfide bond to form a complex of sulfenamide and the proton pump, thereby inhibiting the activity of the enzyme and blocking the final step of gastric acid secretion. Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various reasons.

The main ingredient of this product is omeprazole.

This product is an enteric-coated tablet, which appears white or off-white after removing the coating.

It is suitable for gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and Zollinger-Ellison syndrome (gastrinoma).

Oral administration, do not chew. 1. Peptic ulcer: 20 mg (1 tablet at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course for gastric ulcer is usually 4-8 weeks, and the treatment course for duodenal ulcer is usually 2-4 weeks. 2. Reflux esophagitis: 20-60 mg (1-3 tablets at a time), 1-2 times a day. Swallow in the morning or once in the morning and evening. The treatment course is usually 4-8 weeks. 3. Zollinger-Ellison syndrome: 60 mg (3 tablets at a time), once a day. The total daily dose can be adjusted to 20-120 mg (1-6 tablets) according to the condition. If the total daily dose exceeds 80 mg (4 tablets), it should be taken in two doses.

This product is well tolerated. Common adverse reactions are diarrhea, headache, nausea, abdominal pain, gastrointestinal flatulence and constipation. Occasionally, serum aminotransferase (ALT, AST) increase, rash, dizziness, drowsiness, insomnia, etc. are observed. These adverse reactions are usually mild, disappear automatically, and are not related to the dose.

It is contraindicated for patients who are allergic to this product, those with severe renal insufficiency and infants.

Precautions for children: Not for use in infants and young children. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.

1. Avoid using it at the same time with oral imidazole antifungal drugs such as ketoconazole, itraconazole, miconazole and fluconazole. 2. The combined use of omeprazole and clarithromycin can increase the incidence of adverse reactions in the central nervous system (mainly headache) and gastrointestinal tract. 3. Avoid using it at the same time with diazepam (valium), phenytoin, warfarin, nifedipine, digoxin, cisapride, quinidine cyclosporine, caffeine and theophylline. 4. If used at the same time with other drugs, drug interactions may occur. Please consult your doctor or pharmacist for details.

Keep away from light, sealed and stored in a dry place.

10mg

24 months

Xinhe Yuansheng MEDICINE Co., Ltd.

• Founded in:

  1989-10-20

• Address:

  No. 185, Liaocheng East Road, Gushi County

• Tax NO.:

  91411525706758024M

• Registered Funds:

  84 million yuan

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