Acyclovir dispersible tablets

This product is a synthetic nucleoside antiviral drug that has inhibitory effects on herpes simplex virus type I (HSV-1), type H (HSV-2) and varicella-zoster virus (VZV) both in vivo and in vitro. Cell culture results show that this product has the strongest inhibitory effect on HSV-1 virus, followed by HSV-2 and VZV viruses. Because this product has affinity for thymidine kinase (TK) encoded by HSV and VZV, it has a highly selective inhibitory effect. This type of viral enzyme converts acyclovir into acyclovir monophosphate, a nucleoside analog. The monophosphate is further converted into diphosphate by guanylate kinase in the cell, and then converted into triphosphate by multiple enzymes in the cell. In vitro, acyclovir triphosphate stops herpes virus DNA replication.

The main ingredient of this product is acyclovir, and its chemical name is: 9-[(2-hydroxyethoxy)methyl]guanine

This product is white tablets.

1. Herpes simplex virus infection: used for the initial and recurrent cases of genital herpes virus infection. For recurrent cases, this product can be taken orally for prevention. 2. Herpes zoster: used for the treatment of herpes zoster in people with normal immune function and mild cases in people with immunodeficiency. 3. Treatment of chickenpox in people with immunodeficiency.

Oral, dosage is as follows: This product is a dispersible tablet, which can be taken orally/swallowed directly, or put this product into about 100ml of water, shake to disperse and then take orally. 1 Acute herpes zoster: Adults take 200~800mg each time, once every 4 hours, 5 times a day, for 7~10 days. 2 Genital herpes: Initial genital herpes: Adults take 200mg each time, once every 4 hours, 5 times a day, for 10 days. Chronic recurrent genital herpes: Adults take 200mg~400mg each time, twice a day, continue treatment for 4~6 months or 12 months, and re-evaluate. According to the results of the re-evaluation, choose 200mg each time, 3 times a day, or 200mg each time.

1 Digestive system reactions: including nausea, vomiting, diarrhea, etc. 2 Allergic reactions: including fever, headache, peripheral redness and swelling, etc. 3 Neurological reactions: including headache, overexcitement, ataxia, coma, confusion, decreased consciousness, confusion, dizziness, hallucinations, local paralysis, drowsiness, etc. 4v Blood and lymphatic system: including anemia, leukopenia and thrombocytopenia, etc. 5 Liver, gallbladder, pancreas: including hepatitis, hyperbilirubinemia, jaundice, etc. 6 Muscle and skeletal system: muscle pain reaction. 7 Skin: hair loss, photosensitive rash, pruritus, epidermal necrosis, urticaria

1. It is contraindicated for patients who are allergic to acyclovir.

Precautions for children: The dosage for children under 2 years old has not been determined. Precautions for pregnancy and lactation: The drug can pass through the placenta. Although animal experiments have confirmed that it has no effect on the embryo, pregnant women still need to weigh the pros and cons of using the drug. The concentration of the drug in breast milk is 0.6 to 4.1 times the blood concentration. Although no abnormalities have been found in infants, breastfeeding women should use it with caution. Precautions for the elderly: Due to the decline of physiological renal function, the dosage and medication interval of this product need to be adjusted.

When probenecid is used with intravenous acyclovir, the mean half-life and area under the concentration-time curve of acyclovir are increased.

Sealed and stored in a cool place.

0.1g

24 months

Wuhan Hiteck Biological Pharma Co., Ltd.

• Founded in:

  1992-04-08

• Address:

  Wuhan Economic and Technological Development Zone Haite Technology Park

• Tax NO.:

  91420100724667038L

• Registered Funds:

  130.894391 yuan

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