Secnidazole tablets

[Pharmacology and Toxicology] Huperzine A is a cholinesterase inhibitor, which has a selective inhibitory effect on acetylcholinesterase and can easily pass through the blood-brain barrier. It has the effects of promoting memory retrieval, enhancing memory retention and strengthening muscle contraction strength. [Pharmacokinetics] Due to the extremely small dosage of Huperzine A, there is currently no effective method for drug detection in human pharmacokinetic studies. Studies using rats iv and ig [3H] labeled Huperzine A showed that the pharmacokinetics is an open two-compartment model. iv: t1/2α=6.6min, t1/2szlig;=149min; ig: t1/2α=9.8min, t1/2szlig;=247.5min. The blood drug concentration reaches its peak 21 minutes after ig, the bioavailability is 96.9%, and the 24-hour urine excretion is 73.2% of the dose. Some of it is metabolized into products with greater water solubility and excreted. The plasma protein binding rate is low, at 17±4%. According to the same intensity of action, the ig dose of Huperzine A is about twice that of iv.

The main component is Huperzine A. Chemical name: (5R, 9R, 11E)-5-amino-11-ethylidene-5,8,9,10-tetrahydro-7-methyl-5,9-methylenecyclooctatetraen[b]pyridin-2-(1H)-one.

This product is white freeze-dried block or powder.

This product is suitable for benign memory disorders, improving patients' ability of directed memory, associative learning, image recall, meaningless pattern recognition and portrait recall. It also improves memory disorders caused by dementia patients and organic brain lesions. In addition, this product is also used to treat myasthenia gravis.

Take this product, dissolve each bottle with 2ml sterile water for injection and inject intramuscularly. For the treatment of benign memory impairment: 0.2mg once a day or as directed by a doctor; for the treatment of myasthenia gravis: 0.2-0.4mg once a day or as directed by a doctor.

This product has no obvious adverse reactions, but excessive dosage may cause dizziness, nausea, gastrointestinal discomfort, fatigue, etc. These reactions usually disappear on their own, but in severe cases, atropine can be used to counteract them.

Not yet clear.

Precautions for children: Children over 12 years old can take this product, and the single dose of this product is 30mg/kg, or it can be used under the guidance of a doctor. Precautions for pregnancy and lactation: Women who are pregnant or may become pregnant are prohibited from taking this product; after oral absorption, this product can pass through the placental barrier and enter the breast milk, so lactating women should avoid breastfeeding during medication. Precautions for the elderly: There is currently no information on the use of this product for people over 65 years old.

Not yet clear.

Keep away from light and store in sealed container.

0.5g

24 months