Levodopa tablets
Function and Efficacy
This product is a dopamine-like anti-Parkinson's disease drug. Levodopa is a precursor substance for synthesizing dopamine in the body. It has no pharmacological activity itself. It enters the central nervous system through the blood-brain barrier and is converted into dopamine by dopa decarboxylase to exert its pharmacological effects and improve the symptoms of Parkinson's disease. Since this product can increase neurotransmitters such as dopamine and norepinephrine in the brain, it can also improve the brain's tolerance to ammonia, and is used to treat hepatic coma, improve central nervous system function, make patients sober, and improve symptoms.
Ingredients
A compound tablet composed of two main ingredients: carbidopa and levodopa.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| S-(-)-CarbidopaIngredients |
By inhibiting peripheral dopa decarboxylase, reducing the peripheral metabolism of levodopa, and increasing the amount of levodopa entering the central nervous system, it increases dopamine levels in the brain and improves Parkinson's disease symptoms. More |
28860-95-9 | 8 | |
| LevodopaIngredients |
As a precursor of dopamine synthesis in the body, it enters the central nervous system through the blood-brain barrier and is converted into dopamine by dopa decarboxylase, thus improving the symptoms of Parkinson's disease. At the same time, it can increase neurotransmitters such as dopamine and norepinephrine in the brain, improve the brain's tolerance to ammonia, and is used to treat hepatic coma and improve central nervous system function. More |
59-92-7 | 36 |
Appearance
This product is white or off-white tablets.
Indication
Used for Parkinson's disease and Parkinson's syndrome.
Usage and Dosage
The doctor should make careful adjustments based on the patient's condition to determine the best dose for this product. Common dosage: Oral, half a tablet at a time, 3 times a day. After taking it for a week, increase the dose by half a tablet every 3 to 4 days according to the condition until the best effect is achieved. Patients who are taking levodopa tablets alone should stop taking levodopa tablets for at least 12 hours if they switch to this product. The initial dose calculated based on levodopa should be equivalent to 25% of the original single dose. The maximum daily dose should not exceed 8 tablets (taken in 4 times, 2 tablets each time). Maintenance dose: 3 to 4 times a day, taken in 3 to 4 times.
Adverse Reactions
Common adverse reactions include: nausea, vomiting, orthostatic hypotension, abnormal involuntary movements of the head, face, tongue, upper limbs and upper body, depression, and dysuria. Less common adverse reactions include: hypertension, arrhythmia, and hemolytic anemia.
Precautions
It is contraindicated for patients with severe mental illness, severe arrhythmia, heart failure, glaucoma, peptic ulcer and a history of convulsions.
Special Population Medication
Precautions for children: Use with caution. Precautions for pregnancy and lactation: This product can be secreted into breast milk and can also reduce breast milk secretion; animal experiments have shown that this product can cause visceral and skeletal deformities. Pregnant and lactating women should not use it. Precautions for the elderly: Not yet clear.
Drug Interactions
1. This product combined with non-selective monoamine oxidase inhibitors may cause acute adrenal crisis. 2. This product combined with papaverine or vitamin B6 may reduce the efficacy of this product. 3. This product combined with acetylspiramycin can significantly reduce the blood concentration of this product and weaken the efficacy. 4. This product combined with reserpine can inhibit the effect of this product and should be avoided. 5. This product combined with antipsychotic drugs should be avoided because the two antagonize each other. 6. This product combined with methyldopa can increase the adverse reactions of this product and enhance the antihypertensive effect of methyldopa.
Storage
Keep away from light, tightly closed and in a dry place.
Packaging Specification
0.25g
Validity Period
24 months
Manufacturer
GuangXi HeFeng Pharmaceutical Limited Liability Company
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Founded in:
2000-09-18 -
Address:
Guangxi Donglan County Third Development Zone -
Tax NO.:
914512247188985773 -
Registered Funds:
5.5 million yuan -
Website:
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Email: