Gentomycin Sulfate and Bismuth Carbonate Capsules
Function and Efficacy
Gentamycin sulfate is an aminoglycoside drug. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has certain effects on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has good antibacterial effects on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococci), but methicillin-resistant strains are mostly resistant to this product. It has poor effects on Streptococcus and Streptococcus pneumoniae, and Enterococcus are mostly resistant to this product. This product is combined with β-lactams
Ingredients
This product is a compound preparation, and its components are: each tablet contains 40 mg (40,000 units) of gentamicin sulfate (calculated as gentamicin) and 600 mg of bismuth subcarbonate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Gentamicin sulfateIngredients |
Aminoglycosides have good antibacterial effects on various Gram-negative and Gram-positive bacteria, and have good effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has a certain effect on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has a good antibacterial effect on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococci), but methicillin-resistant strains are mostly resistant to this product. It has a poor effect on Streptococcus and Streptococcus pneumoniae, and Enterococcus is mostly resistant to this product. More |
1405-41-0 | 29 | |
| Bismuth subcarbonateIngredients |
Gentamycin sulfate is an aminoglycoside drug. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has certain effects on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has good antibacterial effects on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococci), but methicillin-resistant strains are mostly resistant to this product. It has poor effects on Streptococcus and Streptococcus pneumoniae, and Enterococcus are mostly resistant to this product. This product is combined with β-lactams More |
5892-10-4 | 8 |
Appearance
This product is a capsule, and the contents are white or slightly yellow powder or granules.
Indication
Used for chronic ulcerative enteritis, dysentery, and acute enteritis.
Usage and Dosage
Oral administration: 2-3 capsules for adults, 3 times a day; 1 capsule for children, 3 times a day. For continuous use, one course of treatment should not exceed 10 days.
Adverse Reactions
1. Nausea, loss of appetite, vomiting, abdominal distension and other gastrointestinal symptoms and skin rash, serum aminotransferase elevation, etc. are rare. 2. Hearing loss, tinnitus or fullness in the ears (ototoxicity), hematuria, significantly reduced urination frequency or urine volume, loss of appetite, extreme thirst (nephrotoxicity), unsteady gait, dizziness (ototoxicity, vestibular effects), dyspnea, drowsiness, extreme weakness (neuro-muscle blockade) are occasionally seen. 3. Long-term use of large doses can cause constipation, alkalosis and malabsorption syndrome.
Precautions
Patients who are allergic to this product or other aminoglycoside antibiotics are contraindicated.
Special Population Medication
Precautions for children: Because this product has potential ototoxicity and nephrotoxicity, it should be used with caution in children. Precautions for pregnancy and lactation: Because the absorbed part of this product can enter the fetal circulation through the placenta, pregnant women should use it with caution. Lactating women should suspend breastfeeding during medication. Precautions for the elderly: Because this product has potential ototoxicity and nephrotoxicity, it should be used with caution in elderly patients.
Drug Interactions
1. When used in combination with other aminoglycosides or when used in sequence, it may increase the possibility of ototoxicity, nephrotoxicity and neuromuscular blocking effects. When used in combination with neuromuscular blockers, it may aggravate neuromuscular blocking effects. 2. When used in combination with capreomycin, cisplatin, ethacrynic acid, furosemide or vancomycin or when used in sequence, it may increase the possibility of ototoxicity and nephrotoxicity. 3. When used in combination with cephalothin, it may increase nephrotoxicity. 4. When used in combination with polymyxins or when used in sequence, it may increase nephrotoxicity and neuromuscular blocking effects. 5. Other nephrotoxic and ototoxic drugs should not be used in combination with this product or when used in sequence, so as not to aggravate nephrotoxicity or ototoxicity. <
Storage
Keep away from light, sealed and stored in a dry place.
Packaging Specification
Gentamycin sulfate 40mg, bismuth subcarbonate 0.6g
Validity Period
Tentative 24 months
Manufacturer
Liaoning Wangpai Quick Result Pharmaceutical Co., Ltd.
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Founded in:
2001-06-20 -
Address:
East Guiyang Road, Jingang Street, Jinzhou Economic and Technological Development Zone, Liaoning Province -
Tax NO.:
9121070012051855XJ -
Registered Funds:
4.134 million yuan -
Email: